دراسة تأثير أوراق بعض النباتات على الفئران المصابة بإرتفاع دهون الدم

Abstract EN

  This study was carried out to evaluate the anti-hypercholesterolemicrats effects of spearmint(Menthe spicataL.

), sage(Salvia officinalis L.

) and okra (Abelmoschusesculentus) leaves.

Thirty two male mature albino rats weighing 150±10g per each, were used in this study and divided into threegroups, the first group was kept as a control (-ve) group (n=4), while the groups were fed on hypercholesterolemicdiet (n=28) for 3 weeks to induce hypercholesterolemicrats.

The tested plant leaves powder (PLP) were given to the rats at the leaves of 3 and 6% from the basel diet for 28 days.

At the end of the experiment, serum total cholesretol(TC), triglycerides(TG), high density lipoprotein (HDL-c), AST, ALT, ALP, urea, creatinin, uric acid were determined Low density lipoprotein(LDL-c), Verylow density lipoprotein (VLDL-c), and Atherogenic index (A.

I) were calculated.

The results indicated that tested plants leaves significantly (P≤0.05) decreased serum TC, TG, LDL.

c, VLDL.

c and increased HDL.

cAlso, the tested plants leaves improved liver and kidney functionsand prevent some of the adverse histopathological changes in heart.

The obtained findingshypothesis that tested plant leavescontaining several compounds those are able to improve the adverse effects hypercholesterolemicdiet.

So, Theobtainedresults recommended such plants by a moderate amount in our diets, are more benefits