The effect of garlic aqueaus extract and garlic, apple and balsamic vinegars to improve the health of ofhypercholesterolemic obese rats

Abstract EN

Obesity has become a major worldwide health problem.

This study was conducted to investigate the effect of garlic aqueous extract and garlic, apple and balsamic vinegars to improve the health of rats infected with obesity and hypercholesterolemia.

Rats were divided into two main group, the first group negative control group (5 rats) fed on basal diet for all experimental period as control negative group.

And obese hypercholestrolemic rats (245–250g) were divided into 4 subgroups (5 per each): subgroup 1 served as positive control group, subgroup 2, 3, 4 and 5 were fedbasal diet and given orally one receives a daily gavage of garlic aqueous extract, garlic vinegar, apple vinegar, balsamic vinegar(7mL/kg/d) for 30 days.

After the end of experiment period, blood samples were collected for used to the biochemical analysis as kidney functions, lipids profileand antioxidant status.

The results indicated that treatments with garlic vinegar, garlic aqueous extract, apple vinegar, balsamic vinegar significantly(p≤0.05) improved lipid profile andkidney and liver functions compared to positive control group.

Inconclusion: Garlic aqueous extract and garlic, apple, balsamic vinegars had improved lipid profile and atherogenic indexes, kidney and liver functions and antioxidant status in hypercholesterolemicobese rats