Hypocholesterolemic effect evaluation of Qaisum, oat bran and mustard when used for Sprague Dawely male Albio rats

Abstract EN

This study aimed to investigate the effect of Oat Bran (Avena sativa), Mustard (Brassica nigra) and Qaisum (Artemisia vulgaris ) on hypercholesterolemic rats induced by cholesterol powder.

Forty five adult male mature evaluated Albino rats, weighing 160-150 g each, were used in this study rats and divided into 9 equal groups.

The first group was kept as a control -ve group, while the other groups were fed on hypercholesterolemic diet for 3 weeks to induce hypercholesterolemic rats.

The tested Oat Bran, Mustard seeds and Qaisum were given to the rats at a percent of 3 and 5 % from the basel diet for 28 days.

At the end of the experiment, serum total cholesretol (TC), triglycerides (TG), high density lipoprotein (HDL-c), GOT, GPT, ALP, urea, creatinine, uric acid were determined.

Low density lipoprotein (LDL-c), very low density lipoprotein (VLDL-c), A.

I and glucose were assessed.

The results of the obtained data indicated that Oat Bran, Mustard and Qaisum significantly (P≤0.05) decreased serum TC, TG, LDL, VLDL and A.

I while increased HDL.

Also, Oat Bran, Mustard and Qaisum diets improved liver and kidney functions.

The obtained findings confirmed the hypothesis that tested plant parts contained several compounds, those are able to ameliorate the adverse effects of raised serum cholesterol and inhibited hypercholesterolemic in rats.

The data recommended such plants by moderate amounts in our diets, to make use of health their benefits.