Study of potential effect of banana flower and papaya leaves in Alloxan-induced diabetic rats

Abstract EN

This study was carried out to evaluate the antihyperglycaemic effects of banana flower (Musa paradisiaca) and papaya leaves (Carica Papaya, Linn) and their mixture as powder in rats.

Forty eight male mature albino rats weighing 150-160g B.

wt.

each, were used in this study and divided into 8 equal groups, each group contain 6 rats, one was kept as a control -ve group, while the other groups were injected by alloxan (150mg/kg body weight).

The tested plants powders were given to the rats as a percent of 2.5% and 5% from the Basel diet.

At the end of the experiment, hematological parameters, (RBC-s, WBC-s, hemoglobin and platelet), serum liver functions (ALT- AST – ALP), total protein, albumin, kidney functions (creatinine, uric acid and urea), total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL-c), low density lipoprotein (LDL-c) and very low density lipoprotein (VLDL-c ) were assessed.

The results of the obtained data indicated that tested plants improved glucose levels, liver functions, kidney functions and lipid profile.

The obtained findings hypothezed that tested plant parts containing several compounds are able to improve the adverse effects and inhibited hyperglycemia in rats.

According to these results, moderate amounts of banana flower and papaya leaves in our diets could be used for improvement glucose level.