Effect of oral administration of paraquat pesticide on the hippocampus and Substantia Nigra in Wistar Rat's brains

Other Title(s)

تأثير التجريع الفموي للمبيد العشبي (الباراكوات)‎ على الحصين و المادة السوداء في أدمغة جرذان الويستر

Joint Authors

Zalan, Ibtihajah Abd al-Razzaq
Tahhan, Zahir Samman
Qasim, Mahmud
Bilal, Muhammad Muayyad

Source

Journal of Agricultural, Environmental and Veterinary Sciences

Issue

Vol. 5, Issue 3 (30 Sep. 2021), pp.71-84, 14 p.

Publisher

National Research Center

Publication Date

2021-09-30

Country of Publication

Palestine (Gaza Strip)

No. of Pages

14

Main Subjects

Agriculture

Abstract EN

This study aimed to detect the neurohistological damages of chronic exposure to low levels of pesticide (paraquat) in the hippocampus, and substantia nigra in Wistar rats' brains.

The neurotoxic effects of acute poisoning are well established but the possibility that low level exposure causes different diseases is controversial.

It is important to get a clear answer to this question as more individuals are at risk of low level exposure than acute poisoning.

The anatomical and histological of current study to affected brains showed cells display the cytological changes of herbisecticides-lesioned brain tissue, such as a significant decrease in the size of the brain was observed, as most of its external features disappeared.

in addition, we detected vacuolization around cells that degenerated because many reasons like apoptosis or necrosis, and the intracellular neurofibrillary tangles were observed at many regions such as the hippocampus and substantia nigra.

Moreover extracellular amyloid plaques take fibers form were detected.

we also observed degenerated in CA1, CA2 and CA3 regions (molecular layer, polymorphic layer and pyramidal layer) by pigmenting degenerated neurons with silver nitrate with increased astrocytes of glia cells.

American Psychological Association (APA)

Zalan, Ibtihajah Abd al-Razzaq& Qasim, Mahmud& Bilal, Muhammad Muayyad& Tahhan, Zahir Samman. 2021. Effect of oral administration of paraquat pesticide on the hippocampus and Substantia Nigra in Wistar Rat's brains. Journal of Agricultural, Environmental and Veterinary Sciences،Vol. 5, no. 3, pp.71-84.
https://search.emarefa.net/detail/BIM-1307870

Modern Language Association (MLA)

Zalan, Ibtihajah Abd al-Razzaq…[et al.]. Effect of oral administration of paraquat pesticide on the hippocampus and Substantia Nigra in Wistar Rat's brains. Journal of Agricultural, Environmental and Veterinary Sciences Vol. 5, no. 3 (Sep. 2021), pp.71-84.
https://search.emarefa.net/detail/BIM-1307870

American Medical Association (AMA)

Zalan, Ibtihajah Abd al-Razzaq& Qasim, Mahmud& Bilal, Muhammad Muayyad& Tahhan, Zahir Samman. Effect of oral administration of paraquat pesticide on the hippocampus and Substantia Nigra in Wistar Rat's brains. Journal of Agricultural, Environmental and Veterinary Sciences. 2021. Vol. 5, no. 3, pp.71-84.
https://search.emarefa.net/detail/BIM-1307870

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 82-84

Record ID

BIM-1307870