Relationship between prostate sspecific antigen and testosterone, insulin, adeponectin on prostate cancer patients with metabolic syndrome

Abstract EN

Prostate cancer (PCa) is a very common visceral malignancy in men it counts about one-third of all male cancers and it is the second cause of cancer death in males in United States of America.

The conduction of this trail is to know the relationship between prostate specific antigen PSA, testosterone T , insulin and adiponectin in prostate cancer patients suffering From metabolic syndrome (MetS).

There is significant difference (p< 0.05) in PSA level (39.04 ± 5.05, 2.93± 0.26) ng/ml respectively in prostate cancer group compared with control group.Significant Difference (p<0.05) in prostate cancer testosterone level (2.44±0.15, 3.10± 0.14) ng/ml respectively compared with control group.Significant difference (p<0.05) in prostate cancer adiponectin level (3.82 ±0.12, 4.50± 0.39) μiu/ml respectively compared with control group.Significant difference (p<0.05) in prostate cancer insulin level (6.13±0.86, 3.77± 0.27) μu/ml respectively compared with control group.

There is weak negative correlation between PSA and T (-0.29).weak negative correlation between PSA and insulin (-0.11).

Correlation between PSA and adiponectin is undetectable.