Dexamethasone treatment and perinatal morbidity and mortality in pregnancies complicated by premature rupture of membranes
Joint Authors
al-Taani, Muhammad
al-Maayitah, Jamal
Qublan, Husayn S. T.
Source
Journal of the Royal Medical Services
Issue
Vol. 7, Issue 2 (31 Dec. 2000), pp.53-58, 6 p.
Publisher
The Royal Medical Services Jordan Armed Forces
Publication Date
2000-12-31
Country of Publication
Jordan
No. of Pages
6
Main Subjects
Topics
Abstract EN
Objective : To determine the effect of antenatal dexamethasone therapy on perinatal morbidity and mortality in pregnancies complicated by premature rupture of membranes.
Methods : This study was performed on one hundred pregnant women between 27-34 weeks of gestation with singleton pregnancy, complicated by premature rupture of membranes over 16 months at Prince Rashid Ben Al-Hassan Hospital Fifty-one women received dexamethasone during their admission, while 49 women (control group) did not All women were examined clinically and the diagnosis of premature rupture of membranes was demonstrated using speculum and Nitrazine paper examination.
All neonates were evaluated clinically, and by doing laboratory and radiological investigations.
The Fisher exact test was used to assess the significance of differences between the two studied groups.
Results : Premature infants of dexamethasone treated women with premature rupture of membranes showed a significant reduction in the incidence of respiratory distress syndrome (P < 0.001) and necrotizing enterocolitis (P < 0.05).
Respiratory distress syndrome was the only significant cause affecting the perinatal morbidity with significant increase in the control group (P < 0.04).
Perinatal mortality was significantly decreased among the dexamethasone group in gestational and birth weight subgroups (P < 0.04).
Postpartum endometritis was significantly increased among the dexamethasone treated group (P < 0.05).
Infants of treated women showed a significant decrease in hospital stay (P < 0.04).
Conclusion : The use of dexamethasone in pregnancies complicated by premature rupture of membranes has a positive effect on premature infants, significantly decreasing the perinatal morbidity.
American Psychological Association (APA)
Qublan, Husayn S. T.& al-Taani, Muhammad& al-Maayitah, Jamal. 2000. Dexamethasone treatment and perinatal morbidity and mortality in pregnancies complicated by premature rupture of membranes. Journal of the Royal Medical Services،Vol. 7, no. 2, pp.53-58.
https://search.emarefa.net/detail/BIM-132220
Modern Language Association (MLA)
Qublan, Husayn S. T.…[et al.]. Dexamethasone treatment and perinatal morbidity and mortality in pregnancies complicated by premature rupture of membranes. Journal of the Royal Medical Services Vol. 7, no. 2 (Dec. 2000), pp.53-58.
https://search.emarefa.net/detail/BIM-132220
American Medical Association (AMA)
Qublan, Husayn S. T.& al-Taani, Muhammad& al-Maayitah, Jamal. Dexamethasone treatment and perinatal morbidity and mortality in pregnancies complicated by premature rupture of membranes. Journal of the Royal Medical Services. 2000. Vol. 7, no. 2, pp.53-58.
https://search.emarefa.net/detail/BIM-132220
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 57-58
Record ID
BIM-132220