Special effects of parsley (petroselinum crispum)‎ on streptozotocin-induced diabetic rats : biochemical profiles

Abstract EN

This study was conducted to evaluate the effect of Parsley (Petroselinum crispum) on some biochemical profiles streptozotocin-induced diabetic rats.

For this purpose, 20 male albino rats were divided into 4 groups according to the program assigned 5 rats per group: Group 1: control group kept on basal ration, Group 2: Parsley group kept on basal ration + Parsley 2gm/kg body weight, Group 3: Diabetic group rats injected intra peritoneal with STZ 45mg/kg body weight and kept on basal diet, Group 4: Diabetic + Parsley rats injected intra peritoneal with STZ 45mg/kg body weight and kept on basal diet + Parsley 2gm/kg body weight.

Results showed that, treatment of the STZ induced diabetic rats with parsley, resulted in significant decrease in fasting blood glucose and glycated hemoglobin compared to control group and there is significant difference within all groups in ALT, AST, Urea and Creatinine also in Total cholesterol and Triglyceride.

In summary, the best results of biochemical profiles in diabetic rats occurred on, diabetic + Parsley rats injected intra peritoneal with STZ 45mg/kg body weight and kept on basal diet + Parsley 2gm/kg body weight.

Henceforth, a clinical could be conducted before general recommendation.