Clinico-biochemical and electrocardiographic changes in cattle naturally infected with lumpy skin disease
Joint Authors
Marwan, Marwan Adil
al-Bahji, Halah E. K.
Hilal, Muhammad A. Y.
Source
Alexandria Journal of Veterinary Sciences
Issue
Vol. 60, Issue 1 (31 Jan. 2019), pp.41-48, 8 p.
Publisher
Alexandria University Faculty of Veterinary Medicine
Publication Date
2019-01-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Lumpy skin disease (LSD) is an economically important viral disease of cattle caused by Capripox virus.
The disease is characterized clinically by fever, nodules on the skin, mucous membranes and internal organs, emaciation, enlarged lymph nodes, edema of the skin and deaths in some cases.
The aim of this study is to investigate the clinico- biochemical picture of LSD infected cattle with special reference to the cardiac abnormalities.
This study was carried out on LSD infected cattle showing typical clinical signs of the disease in Kaliobia governorate (n = 50; and aged between 2 to 5 years old).
Clinical and electrocardiographic examination (ECG) were performed firstly, then skin nodules were aseptically collected from infected cattle for molecular detection of LSDV using PCR, on the other hand, serum samples were collected for biochemical analysis.
The results of the current study revealed that, all the examined tissue samples showed successful amplification of the viral attachment protein gene of LSDV with presence of positive bands at the target size (192 bp).
Furthermore, troponin I (cTnI), urea, creatinine ALT, AST, ALP and potassium were significantly increased in LSD infected cattle compared to the control ones.
In contrast, serum calcium, iron and sodium concentrations were significantly decreased.
The ECG of LSD infected cattle showed abnormal P waves, shortening of P and T-waves amplitudes and decrease in RT interval compared to healthy cattle.
The cardiac alterations in case of LSD infection could be related to the elevation of cTnI because of direct effect of the virus on the heart beside electrolyte imbalance, acidosis and hypocalcaemia.
American Psychological Association (APA)
Hilal, Muhammad A. Y.& Marwan, Marwan Adil& al-Bahji, Halah E. K.. 2019. Clinico-biochemical and electrocardiographic changes in cattle naturally infected with lumpy skin disease. Alexandria Journal of Veterinary Sciences،Vol. 60, no. 1, pp.41-48.
https://search.emarefa.net/detail/BIM-1327475
Modern Language Association (MLA)
Hilal, Muhammad A. Y.…[et al.]. Clinico-biochemical and electrocardiographic changes in cattle naturally infected with lumpy skin disease. Alexandria Journal of Veterinary Sciences Vol. 60, no. 1 (Jan. 2019), pp.41-48.
https://search.emarefa.net/detail/BIM-1327475
American Medical Association (AMA)
Hilal, Muhammad A. Y.& Marwan, Marwan Adil& al-Bahji, Halah E. K.. Clinico-biochemical and electrocardiographic changes in cattle naturally infected with lumpy skin disease. Alexandria Journal of Veterinary Sciences. 2019. Vol. 60, no. 1, pp.41-48.
https://search.emarefa.net/detail/BIM-1327475
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 46-48
Record ID
BIM-1327475