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Clinical evaluation of intravenous propofol alone or in combination with diazepam, ketamine Hcl and thiopental sodium to induce general anaesthesia in dogs
Joint Authors
al-Kammar, Mahmud H.
Shaaban, Maha F.
Quraytim, Sharif A.
Qasim, Mustafa M.
Source
Alexandria Journal of Veterinary Sciences
Issue
Vol. 57, Issue 1 (30 Apr. 2018), pp.106-114, 9 p.
Publisher
Alexandria University Faculty of Veterinary Medicine
Publication Date
2018-04-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
This study aimed to evaluate hemato-biochemial and clinico-physiological effects in addition to the anesthetic properties of propofol alone or in combination with diazepam, ketamine Hcl or thiopental sodium.
For this purpose, 12 apparently healthy male dogs were randomly divided into four equal groups; A, B, C and D.
All dogs were permedicated with xylazine Hcl (1mg/kg Bwt/IM) then intravenous anesthesia was induced in group A with(5 mg/kg Bwt)propofol or with propofol and ketamine hydrochloride mixture( 2mg/kg Bwt of each drug in group B ,or with propofol and thiopental mixture (2.5 mg/kg propofol and 6,5 mg/kg thiopental) in group c while group D receveid propofol (2mg/kg Bwt) followed 0.2mg/kg Bwt diazepam.
Blood samples were collected from the four groups 15 minutes before anesthesia induction, then at (15, 45, 75 and 120) minutes after treatments for the hemato-biochemical evaluation, also clinico-physiological observations were recorded at the same previous times.
A slight alterations in some physiological parameters and hemato-biochemical values was observed after anesthesia induction in the four groups, but it still safe to induce general anesthesia in dogs.
However propofol –thiopental mixture showed longest anesthesia duration with complete muscle relaxation and sedation that is suitable for most surgical operations.
American Psychological Association (APA)
Shaaban, Maha F.& Qasim, Mustafa M.& al-Kammar, Mahmud H.& Quraytim, Sharif A.. 2018. Clinical evaluation of intravenous propofol alone or in combination with diazepam, ketamine Hcl and thiopental sodium to induce general anaesthesia in dogs. Alexandria Journal of Veterinary Sciences،Vol. 57, no. 1, pp.106-114.
https://search.emarefa.net/detail/BIM-1330075
Modern Language Association (MLA)
Quraytim, Sharif A.…[et al.]. Clinical evaluation of intravenous propofol alone or in combination with diazepam, ketamine Hcl and thiopental sodium to induce general anaesthesia in dogs. Alexandria Journal of Veterinary Sciences Vol. 57, no. 1 (Apr. 2018), pp.106-114.
https://search.emarefa.net/detail/BIM-1330075
American Medical Association (AMA)
Shaaban, Maha F.& Qasim, Mustafa M.& al-Kammar, Mahmud H.& Quraytim, Sharif A.. Clinical evaluation of intravenous propofol alone or in combination with diazepam, ketamine Hcl and thiopental sodium to induce general anaesthesia in dogs. Alexandria Journal of Veterinary Sciences. 2018. Vol. 57, no. 1, pp.106-114.
https://search.emarefa.net/detail/BIM-1330075
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 113-114
Record ID
BIM-1330075