The role of sesame and rice bran oils in treating of cold air-induced pneumonia in experimental rats

Abstract EN

Pneumonia means lung inflammation.

It is the largest infectious reason for killing adults and children.

Aims: the main purpose of this work was to investigate the role of sesames oil (SO) and rice bran oil (RBO) against pneumonia induced by exposure to the cold air and histopathology abnormalities in Waster male rats.

Methods: G1: received only placebo treatment for 21 days; G 2: was exposed to low- temperature degree 4-5 °C.

G3 ingested orally SO 5.0 g/ K.

g.

bw.

G4: exposed to cold plus was given SO 5.0 g/ K.

g.

bw.

G5: ingested orally RBO 5.0 g/ K.

g.

bw.

G6: exposed to cold plus was given RBO 5.0 g/ K.

g.

bw.

G7: exposed to cold plus fed the mixture of SO+ RBO 5.0 g/ K.

g.

bw (50% of each other).

Results: the group of rats treated SO & RBO, (G3to G7) have significantly improved (p≤0.05) in feed intake, BWG % , lung wt.

, HB, WBC, and glucose, compared with group 2.

The results indicated the levels of C- reactive protein (CRP), interleukin-1 alpha (IL-1β), interleukin-4 alpha (IL-4) and, tumor necrosis factor (TNF-α), and IgE, were increased significantly (p≤0.05) in (G2) compared to all treated groups with SO / RBO or mixtures and histopathology supported these results.

Conclusion: SO / RBO or mixtures lessen the oxidative process in blood and lung tissue, inflammation markers, cytokine, and IgE levels.

So must be included in diet and processing food, especially in infants, children, and elderly persons.

It May be recommended in diet the inflammatory diseases, allergy, and diabetes.