Second-trimester maternal serum double-test screening for down syndrome
Joint Authors
Source
Journal of the Royal Medical Services
Issue
Vol. 9, Issue 1 (30 Jun. 2002), pp.12-15, 4 p.
Publisher
The Royal Medical Services Jordan Armed Forces
Publication Date
2002-06-30
Country of Publication
Jordan
No. of Pages
4
Main Subjects
Topics
Abstract EN
Objective : The purpose of the study was to determine the detection rate of Down syndrome using the double- test; Alfa-feto protein and human chorionic gonadotropin.
Methods : Five thousand three hundred and thirty pregnant women below the age of 35, were screened between November 1998 and October 1999 at Birmingham Women's Hospital, U.K.
They were singletons and without risk factors for chromosomal abnormalities.
Results : Two hundred and twenty patients (4.1 %) were initially classified as screen positive.
After revision of gestation by ultra-sound, 159 (3 %) were true screen positive.
Eight were affected by Down syndrome and all selected pregnancy termination after counseling.
The odds of being affected given a positive screen result was 1 in 33.
Three affected pregnancies were missed.
The detection rate was 57 %.
Conclusion : The study of second- trimester double-test screening for fetal Down syndrome was acceptable to be usedfor all pregnant women below the age of 35.
American Psychological Association (APA)
Barqawi, Rafiq& Mann, Catherine. 2002. Second-trimester maternal serum double-test screening for down syndrome. Journal of the Royal Medical Services،Vol. 9, no. 1, pp.12-15.
https://search.emarefa.net/detail/BIM-133700
Modern Language Association (MLA)
Barqawi, Rafiq& Mann, Catherine. Second-trimester maternal serum double-test screening for down syndrome. Journal of the Royal Medical Services Vol. 9, no. 1 (Jun. 2002), pp.12-15.
https://search.emarefa.net/detail/BIM-133700
American Medical Association (AMA)
Barqawi, Rafiq& Mann, Catherine. Second-trimester maternal serum double-test screening for down syndrome. Journal of the Royal Medical Services. 2002. Vol. 9, no. 1, pp.12-15.
https://search.emarefa.net/detail/BIM-133700
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 14-15
Record ID
BIM-133700