Metronidazole-induced cerebellar neurotoxicity

Abstract EN

Unintentional overuse of commonly prescribed medications can prove catastrophic.

a 30-year-old man presented with difficulty in speaking and walking since 10 days.

examination revealed ataxic gait and bilateral cerebellar signs.

during a recent admission for amoebic liver abscess, he was managed with the percutaneous aspiration of abscess and metronidazole which he continued for more than 2 weeks.

during the current presentation, brain imaging showed confluent hypodensities in the bilateral dentate nucleus suggestive of metronidazole toxicity.

two weeks after discontinuation of the offending agent, the patient improved clinically with complete radiological resolution of lesions.