A review on clinical, pathological characteristics and drug designing for COVID-19
Joint Authors
Mukhtar, Hamid
Ashraf, Muhammad Usamah
Sharif, Sundus
Ahmad, Muhammad Uthman
Zahid, Muhammad Numan
Source
Arab Journal of Basic and Applied Sciences
Issue
Vol. 28, Issue 1 (31 Dec. 2021), pp.172-186, 15 p.
Publisher
University of Bahrain College of Science
Publication Date
2021-12-31
Country of Publication
Bahrain
No. of Pages
15
Main Subjects
Abstract EN
In late 2019, a novel strain of coronavirus (2019-nCoV) named as severe respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, a city in China, through some zoonotic reservoir, most probably a bat, and spread throughout the world.
There have been around 22,213,869 reported cases of COVID-19 and almost 781,677 deaths worldwide according to the data updated by World Health Organization till 20 August 2020.
It transmitted via droplets from an infected person to a healthy person in a very short duration of time.
After the completion of the incubation period, which ranges from 2 to 14 days, the person experiences pneumonia-like symptoms such as fever, sore throat, cough, breathlessness, malaise, fatigue, and multi-organ dysfunction, etc.
The main receptor of SARS-CoV-2 is angiotensin-converting enzyme 2 which binds with the spike (S) protein of the virus and helps it in attachment and entry to the host cells.
COVID-19 is diagnosed by molecular testing of respiratory secretions and CT scan analysis.
Because of the absence of any approved treatment options for COVID-19, a number of research studies are being carried out to find out any combination of already approved drugs or new lead compounds using in silico docking and screening strategies.
American Psychological Association (APA)
Ashraf, Muhammad Usamah& Sharif, Sundus& Ahmad, Muhammad Uthman& Zahid, Muhammad Numan& Mukhtar, Hamid. 2021. A review on clinical, pathological characteristics and drug designing for COVID-19. Arab Journal of Basic and Applied Sciences،Vol. 28, no. 1, pp.172-186.
https://search.emarefa.net/detail/BIM-1340622
Modern Language Association (MLA)
Ashraf, Muhammad Usamah…[et al.]. A review on clinical, pathological characteristics and drug designing for COVID-19. Arab Journal of Basic and Applied Sciences Vol. 28, no. 1 (2021), pp.172-186.
https://search.emarefa.net/detail/BIM-1340622
American Medical Association (AMA)
Ashraf, Muhammad Usamah& Sharif, Sundus& Ahmad, Muhammad Uthman& Zahid, Muhammad Numan& Mukhtar, Hamid. A review on clinical, pathological characteristics and drug designing for COVID-19. Arab Journal of Basic and Applied Sciences. 2021. Vol. 28, no. 1, pp.172-186.
https://search.emarefa.net/detail/BIM-1340622
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 183-186
Record ID
BIM-1340622