TORCH infections, pathogenicity and mortality assessments

Abstract EN

A TORCH infection, also known as torch syndrome, is an infection of the developing fetus or newborn that can occur in utero, during delivery, or after birth.

TORCH syndrome is a cluster of symptoms caused by congenital infection with toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and other organisms including syphilis, parvovirus, and varicella zoster as well as Zika virus and others.

TORCH syndrome is caused by in-utero infection with one of the TORCH agents, disrupting fetal development.

early diagnosis by specific IGM and persistence of igg beyond 6-9 months is diagnostic.

TORCH syndrome may develop before birth, causing stillbirth, in the neonatal period, or later in life, refers very broadly pathogens that cause perinatal infection and contribute to neonatal morbidity and mortality.

they can cause non-specific signs and symptoms in the fetus or infant, such as microcephaly, lethargy, cataracts, hearing loss, and congenital heart diseases.

other signs include hepatosplenomegaly, petechiae or purpura, jaundice, vision loss, intellectual disability, deafness, and seizures.

treatment of pregnancy women is supportive and depends on symptoms present and thereby preventing the infection from affecting the fetus.