Syndrome of inappropriate antidiuretic hormone secretion in a patient with uncontrolled tyrosinaemia type 1
Joint Authors
al-Thihli, Khalid
al-Murshidi, Fathiyah
al-Hanai, Abd al-Hamid
al-Nabhani, Dana
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 21, Issue 2 (31 May. 2021), pp.312-315, 4 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2021-05-31
Country of Publication
Oman
No. of Pages
4
Main Subjects
Abstract EN
Syndrome of inappropriate antidiuretic hormone (SIADH) secretion is a recognisable complication of acute porphyria.
We report a nine-year-old female patient with hereditary tyrosinaemia type 1 and poor adherence to nitisinone therapy who presented with acute abdominal pain, vomiting and lethargy at Sultan Qaboos University Hospital, Muscat, Oman in 2016.
she subsequently developed generalised tonic-clonic seizures attributable to severe hyponatremia that met the diagnostic criteria of SIADH.
the acute porphyria screen also appeared positive.
the patient responded well to fluid restriction and was discharged home without immediate neurological sequelae.
although acute porphyria is also a recognised complication of uncontrolled tyrosinaemia type 1, to the best of the authors’ knowledge, no patient with tyrosinaemia type 1 has been reported to present with SIADH.
American Psychological Association (APA)
al-Hanai, Abd al-Hamid& al-Murshidi, Fathiyah& al-Nabhani, Dana& al-Thihli, Khalid. 2021. Syndrome of inappropriate antidiuretic hormone secretion in a patient with uncontrolled tyrosinaemia type 1. Sultan Qaboos University Medical Journal،Vol. 21, no. 2, pp.312-315.
https://search.emarefa.net/detail/BIM-1344169
Modern Language Association (MLA)
al-Hanai, Abd al-Hamid…[et al.]. Syndrome of inappropriate antidiuretic hormone secretion in a patient with uncontrolled tyrosinaemia type 1. Sultan Qaboos University Medical Journal Vol. 21, no. 2 (May. 2021), pp.312-315.
https://search.emarefa.net/detail/BIM-1344169
American Medical Association (AMA)
al-Hanai, Abd al-Hamid& al-Murshidi, Fathiyah& al-Nabhani, Dana& al-Thihli, Khalid. Syndrome of inappropriate antidiuretic hormone secretion in a patient with uncontrolled tyrosinaemia type 1. Sultan Qaboos University Medical Journal. 2021. Vol. 21, no. 2, pp.312-315.
https://search.emarefa.net/detail/BIM-1344169
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 315
Record ID
BIM-1344169