Short-term outcomes of atosiban in the treatment of preterm labour at the Sultan Qaboos University Hospital, Muscat, Oman : a tertiary care experience
Joint Authors
Pillai, Silja A.
Jaju, Sanjay
al-Badri, Hanin
al-Riyami, Nihal
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 21, Issue 2 (31 May. 2021), pp.260-265, 6 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2021-05-31
Country of Publication
Oman
No. of Pages
6
Main Subjects
Abstract EN
Objectives : this study aimed to generate baseline evidence regarding the effectiveness of atosiban in delaying delivery by ≥48 hours among pregnant women presenting with threatened preterm labour (TPL).
the secondary objective was to assess the relationship between atosiban success and various perinatal factors and neonatal outcomes.
Methods : this retrospective study was conducted between June 2008 and May 2018 at the Sultan Qaboos University Hospital, Muscat, Oman.
the medical records of all pregnant women who received atosiban between 24–34 gestational weeks for TPL during this period were reviewed.
results : a total of 159 women were included in the study.
Atosiban was successful in delaying delivery by ≥48 hours in 130 cases (81.8%).
approximately half of the women (50.9%) achieved uterine quiescence in <12 hours.
failure to delay delivery by ≥48 hours was significantly lower among women with normal versus abnormal cervical findings (11.1% versus 25.6% ; P = 0.023).
only 9.4% of women experienced minor side-effects.
mean birth weight (2,724.55 versus 1,707.59 g ; P <0.001) and Apgar scores at 5 minutes (9.66 versus 8.28; P <0.001) were significantly higher among neonates delivered at ≥48 versus <48 hours post-atosiban, whereas the rate of neonatal respiratory distress syndrome was significantly lower (18.4% versus 81.6% ; P <0.001).
conclusion : atosiban was highly effective in delaying delivery by ≥48 hours and resulted in few adverse maternal side-effects and neonatal outcomes.
to the best of the authors’ knowledge, this is the first study conducted in Oman to evaluate the effectiveness of atosiban in preventing preterm labour.
American Psychological Association (APA)
al-Riyami, Nihal& al-Badri, Hanin& Jaju, Sanjay& Pillai, Silja A.. 2021. Short-term outcomes of atosiban in the treatment of preterm labour at the Sultan Qaboos University Hospital, Muscat, Oman : a tertiary care experience. Sultan Qaboos University Medical Journal،Vol. 21, no. 2, pp.260-265.
https://search.emarefa.net/detail/BIM-1344833
Modern Language Association (MLA)
al-Riyami, Nihal…[et al.]. Short-term outcomes of atosiban in the treatment of preterm labour at the Sultan Qaboos University Hospital, Muscat, Oman : a tertiary care experience. Sultan Qaboos University Medical Journal Vol. 21, no. 2 (May. 2021), pp.260-265.
https://search.emarefa.net/detail/BIM-1344833
American Medical Association (AMA)
al-Riyami, Nihal& al-Badri, Hanin& Jaju, Sanjay& Pillai, Silja A.. Short-term outcomes of atosiban in the treatment of preterm labour at the Sultan Qaboos University Hospital, Muscat, Oman : a tertiary care experience. Sultan Qaboos University Medical Journal. 2021. Vol. 21, no. 2, pp.260-265.
https://search.emarefa.net/detail/BIM-1344833
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 264-265
Record ID
BIM-1344833