Cataract surgery and intraocular pressure

Abstract EN

Objectives: To analyze the effect of cataract surgery on intraocular pressure (IOP) in patients diagnosed with ocular hypertension (OHT), glaucoma (mild, moderate, and severe),and those without glaucoma (controls).

Methods: In this retrospective study, 236 controls (Group A), 39patients with OHT (Group B), and 101 patients with POAG (mild, moderate, severe; Groups C-E) were recruited at a university eye clinic.

Exclusion criteriawere:<18 years, secondary glaucoma, one functional eye, or follow-up <3 months.

Postoperative IOP was measured at several intervals.

Statistical analyses included linear trends,Chi-squared analyses, Wilcoxon Rank-Sum test for postoperative changes, andmultiple linear regression for predictors of IOP change.

Results: IOP reduction at one year in Groups A-Ewas 8.6% (p<0.001), 8.1% (p=0.061), 10.8% (p=0.047), 18.3% (p=0.135), and 9.1% (p=0.259), respectively.

In Group A, higher preoperative IOP and thicker CCT were predictive of IOP reduction (β= -0.53, -0.02, respectively; p<0.05).

Group B did not show any predictive factors.

In Groups C-E combined, higher preoperative IOP and more glaucoma medications were predictive of IOP reduction at one year (β= -0.66, -1.68, respectively; p<0.05).Medication burdenremained unchanged.

Conclusion: In our population, all groups showed reduction of IOP after cataract surgery at one year.Influential factors in glaucomatous eyes were higher preoperative IOP and increased number of anti-glaucoma medications; higherpreoperative IOP and thicker CCT were significantin controls.

No factors were found to determine IOP reduction in patients with OHT.