Molecular study for mitochondrial gene (MT)‎ mutation in diabetes patients in Karbala province

Abstract EN

Mutations in mitochondrial DNA (mtDNA) associated with various disease states.

A few mtDNA mutations strongly associate with diabetes, such as MT gene mutation .in this study include (48) patients from T2D and T1D compared with (24) healthy ,the patient subject scanned and show mutation in MT gene (422 bp) ,appositive significant relationship between mutation and sex ,age ,family history ,duration of diabetes, marriage and another disease while non-significant relationship between relative and non-relative marriage.