Stenotrophomonas maltophilia : an emerging opportunistic nosocomial pathogen in a tertiary care hospital in Al Batinah North Governorate, Oman

Other Title(s)

الستينوتروفوموناس مالتوفيليا : أحد مسببات الأمراض الانتهازية الناشئة في مستشفيات الرعاية الثالثية في محافظة شمال الباطنة، عمان

Joint Authors

Nambiar, Vinod
Sannathimmappa, Mohan B.
Aravindakshan, Rajeev
al-Kasabi, Nashwa Muhammad

Source

Sultan Qaboos University Medical Journal

Issue

Vol. 21, Issue 1 (28 Feb. 2021), pp.66-71, 6 p.

Publisher

Sultan Qaboos University College of Medicine and Health Sciences

Publication Date

2021-02-28

Country of Publication

Oman

No. of Pages

6

Main Subjects

Economics & Business Administration

Abstract EN

Objectives: Stenotrophomonas maltophilia, a Gram-negative non-fermentative bacillus, has emerged as an important nosocomial pathogen in recent years.

It is intrinsically resistant to many antibiotics and has the ability to acquire antibiotic resistance by multiple mechanisms.

Treating Stenotrophomonas infections, therefore, is a serious challenge for physicians.

This study aimed to investigate the antibiotic susceptibility patterns and risk factors contributing to S.

maltophilia infections.

Methods: A retrospective cross-sectional study was conducted at Sohar Hospital in Sohar, Oman.

The demographic, clinical and microbiological data of individuals from whom S.

maltophilia was isolated between September 2016 and August 2019 were reviewed.

Descriptive statistics were presented as frequencies and percentages.

Results: A total of 41 S.

maltophilia isolates from clinical specimens of 41 patients were studied.

Infection occurred predominantly in males (73%) and the majority of patients (88%) were either ≤5 years old or >60 years old.

All inpatients had at least one comorbidity while 50% had more than one.

All inpatients were exposed to various medical interventions such as intensive care (44%), mechanical ventilation (41%), haemodialysis (25%), Foley’s catheterisation (13%) and central venous lines (6%).

Most patients (81%) were in hospital longer than two weeks.

The susceptibility rates of S.

maltophilia to minocycline (97%), trimethoprimsulfamethoxazole (93%) and levofloxacin (92%) were high; the rate was lowest for ceftazidime (50%).

Conclusion: S.

maltophilia was found to be an important nosocomial opportunistic pathogen.

Prolonged hospital stay and exposure to various medical interventions were key factors contributing to the development of infection.

Minocycline and ceftazidime were found to be the most and least susceptible drugs, respectively.

American Psychological Association (APA)

Sannathimmappa, Mohan B.& Nambiar, Vinod& Aravindakshan, Rajeev& al-Kasabi, Nashwa Muhammad. 2021. Stenotrophomonas maltophilia : an emerging opportunistic nosocomial pathogen in a tertiary care hospital in Al Batinah North Governorate, Oman. Sultan Qaboos University Medical Journal،Vol. 21, no. 1, pp.66-71.
https://search.emarefa.net/detail/BIM-1349542

Modern Language Association (MLA)

Sannathimmappa, Mohan B.…[et al.]. Stenotrophomonas maltophilia : an emerging opportunistic nosocomial pathogen in a tertiary care hospital in Al Batinah North Governorate, Oman. Sultan Qaboos University Medical Journal Vol. 21, no. 1 (Feb. 2021), pp.66-71.
https://search.emarefa.net/detail/BIM-1349542

American Medical Association (AMA)

Sannathimmappa, Mohan B.& Nambiar, Vinod& Aravindakshan, Rajeev& al-Kasabi, Nashwa Muhammad. Stenotrophomonas maltophilia : an emerging opportunistic nosocomial pathogen in a tertiary care hospital in Al Batinah North Governorate, Oman. Sultan Qaboos University Medical Journal. 2021. Vol. 21, no. 1, pp.66-71.
https://search.emarefa.net/detail/BIM-1349542

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 70-71

Record ID

BIM-1349542