Vitamin D deficiency in patients with systemic lupus erythematosus in Suez canal university hospital
Joint Authors
Mutawi, Nada A.
Umar, Hanan Hasan
Tawfiq, Jamal A.
Salim, Ayman
Source
Suez Canal University Medical Journal
Issue
Vol. 25, Issue 1 (31 Mar. 2022), pp.114-124, 11 p.
Publisher
Suez Canal University Faculty of Medicine
Publication Date
2022-03-31
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Topics
Abstract EN
Background : systemic lupus erythematosus (SLE) is a multi-system chronic inflammatory auto-immune disease that compromises multiple organs and unpredictable course and prognosis.
vitamin D deficiency is implicated as a potential environmental factor triggering some autoimmune disorders, including SLE.
aim : to improve the management of SLE patients and reduce disabilities arising as a consequence of vitamin D deficiency.
objectives : our objectives were to assess the prevalence of vitamin D deficiency in SLE patients and its relation to disease activity and renal involvement in those patients.
patients and methods : we enrolled 72 SLE patients who fulfilled the revised classification criteria of the American college of rheumatology whose ages were above or equal to 16 from both genders and who visited the outpatient clinic or were admitted to the inpatient departments of the Suez canal university hospital.
they were subjected to full medical history, examination, SLE disease activity index–sledai-score assessment, and lab in-vestigations (CBC, C3, C4, ESR, urine analysis, 24-hour urine protein, and vitamin D.
results : the mean of vitamin d level was nearly 19 ng / ml ranging from 5 to 38 ng / ml and 55.6% of the patients showed deficient level (< 20 ng / ml).
our variables (disease activity, renal involvement, age, gen-der, BMI, and laboratory findings) were not correlated to vitamin d level except for disease du-ration which showed a strong negative relationship where vitamin d deficiency is remarkable when SLE duration exceeds 6 years (100%) "R = - 0.797 and p > 0.001".
conclusion : vitamin D deficiency is a common problem in SLE patients, also vitamin D deficiency was related to disease du-ration but not to disease activity or renal involvement.
American Psychological Association (APA)
Mutawi, Nada A.& Tawfiq, Jamal A.& Umar, Hanan Hasan& Salim, Ayman. 2022. Vitamin D deficiency in patients with systemic lupus erythematosus in Suez canal university hospital. Suez Canal University Medical Journal،Vol. 25, no. 1, pp.114-124.
https://search.emarefa.net/detail/BIM-1374791
Modern Language Association (MLA)
Mutawi, Nada A.…[et al.]. Vitamin D deficiency in patients with systemic lupus erythematosus in Suez canal university hospital. Suez Canal University Medical Journal Vol. 25, no. 1 (2022), pp.114-124.
https://search.emarefa.net/detail/BIM-1374791
American Medical Association (AMA)
Mutawi, Nada A.& Tawfiq, Jamal A.& Umar, Hanan Hasan& Salim, Ayman. Vitamin D deficiency in patients with systemic lupus erythematosus in Suez canal university hospital. Suez Canal University Medical Journal. 2022. Vol. 25, no. 1, pp.114-124.
https://search.emarefa.net/detail/BIM-1374791
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 122-124
Record ID
BIM-1374791