Effect of aqueous extract of chlorella sp. on entamoeba histolytica parasite in vivo
Joint Authors
Abd al-Wahhab, R. A.
Khadijah A. T.
Fadil, A. M.
Source
Journal of College of Education for Pure Sciences
Issue
Vol. 11, Issue 1 (30 Jun. 2021), pp.41-46, 6 p.
Publisher
University of Thi-Qar College of Education for Pure Sciences
Publication Date
2021-06-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
The objective of this study was to conduct in vivo to detect the effect of Chlorella extract on Entamoeba histolytica.
and to examine its therapeutic effect in male laboratory rats type Mus musculus.
These rats were dosed with a concentration of (1, 1.5 and 2) mg/ml of the aforesaid extract at a daily dose of (10, 15 and 20) days and then, the rats’ faeces were tested to observe the change in parasite numbers after dosing the extract.
The results showed that the aqueoueous extract of Chlorella sp.
was effective in reducing the vesicated and fed stages Entamoeba histolytica-infected rats, where the rate of killing those stages had recorded the highest percentage at dose of 2mg/ml during a period of 20 days.
Moreover, qualitative detections of chemicals for secondary metabolism of aqueoueous extract of Chlorella sp.
were carried out, which indicated the presence of chemically active compounds.
The therapeutic efficiency of the extract was also calculated, which has recorded 62.70%.
Chemical compounds were diagnosed using the gas chromatography technique - gas chromatography mass spectrometry (Gc -mass).
These compounds were represented by 1- (5-Bicyclo [2.2.1] heptyl) ethylamine, 1.4-Bis [5- [3-trifluoromethylphenyl].
1, 2,4-oxadiazol-3-yl] benzene Pentadeoanoic, acid, Estra-1,3,5 (10) -trin-17.
beta.
-0l, 1-Heneicosanol, 1,2,4-Triazol, 4 - [N- (2- hydroxyethyl) -N-nitro] amino-, 9,12-Octadecadienoic acid (Z, Z), 6-octadecadienoic acid, (Z) -, 9-Oxa- bicyclo [3.3.1] Noonan-2,6-dione, cyclopentanicarboxylic acid, 2-acetyl-5-methyl-).
American Psychological Association (APA)
Abd al-Wahhab, R. A.& Fadil, A. M.& Khadijah A. T.. 2021. Effect of aqueous extract of chlorella sp. on entamoeba histolytica parasite in vivo. Journal of College of Education for Pure Sciences،Vol. 11, no. 1, pp.41-46.
https://search.emarefa.net/detail/BIM-1382050
Modern Language Association (MLA)
Abd al-Wahhab, R. A.…[et al.]. Effect of aqueous extract of chlorella sp. on entamoeba histolytica parasite in vivo. Journal of College of Education for Pure Sciences Vol. 11, no. 1 (Jun. 2021), pp.41-46.
https://search.emarefa.net/detail/BIM-1382050
American Medical Association (AMA)
Abd al-Wahhab, R. A.& Fadil, A. M.& Khadijah A. T.. Effect of aqueous extract of chlorella sp. on entamoeba histolytica parasite in vivo. Journal of College of Education for Pure Sciences. 2021. Vol. 11, no. 1, pp.41-46.
https://search.emarefa.net/detail/BIM-1382050
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 45-46
Record ID
BIM-1382050