Influence of oral bisphosphonate on dental implant : a review

Abstract EN

Background : bisphosphonates (BPs) are medications employed widely in the management of metabolic bone diseases.

dental implants are new therapy for replacement of missing teeth depend on the osseointegration process.

there is a considerable debate on the effect of oral BPs on the osseointegration process and subsequently on the success rate of dental implant and development of BRNOJ.

objectives : the aim of this study was to revise literatures on the effect of oral (BPs) on the success rate of dental implants and the development of BPs-related osteonecrosis of the jaws.

materials and methods : pubmed, google scholar, scopus database, and manual search were performed to find out articles on the effect of oral BPs on dental implant outcome and development of BRNOJ.

results : twelve articles were found six retrospective studies, one prospective studies, two case control studies and one case series discussing the effect of oral BPs on success rate of dental implant and development of BRNOJ.

conclusion : the majority of patients were osteoporotic females and treated with oral BPs.

oral BPs have little, if any, influence on success rate of dental implant and there is no conclusive evidence on BRNOJ-related oral BPs in implanted patients.

patients on bps and received implant therapy should be cautioned on developing BRNOJ and followed-up for long time period.