Effect of helicobacter pylori infection on interleukin-4 and interleukin-8 levels in smoker males
Other Title(s)
تأثري عدوى هيلكوباكرت بيلوري على انترلوكين -4 و مستويات انترلوكين-8 في الذكور المدخنين
Author
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 29, Issue 1 (30 Apr. 2021), pp.97-106, 10 p.
Publisher
Publication Date
2021-04-30
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Background: Smoking is a risk factor for various chronic diseases (including various infections, cancer, heart disease and respiratory diseases), and is characterized by neutrophil inflammation and the release of pro-inflammatory mediators (such as IL-8 and IL-4).
Smoking has been found to be associated with higher incidence of Helicobacter pylori and gastroduodenal diseases caused by this bacterium are a consequence of an inappropriate host's immune response.
Materials& Methods: This study aimed to study the effect of smoking on certain immunological parameters, and it is a risk factor for H.
pylori infection in Erbil city.
The study was carried out on 71 smoker males and 20 nonsmokers.
H.
pylori infection and the concentration of IL-4 and IL-8 were done by ELISA Technique.
P values <0.05 were considered statistically significant.
Results: Of the 91males participants, 71 (78%) were smokers and 20 (22%) were non-smoker.
The mean age of smoker men was 24.37±6.52 and 23±4.67 for non-smoker men.
The prevalence rate of H.
pylori infection was significantly higher (P value:0.02) in smoker males 65(9.5%) than non-smoker males12 (6.9%).
Levels of IL-4 and IL-8 were significantly higher in smoker males when compared with nonsmoker males (P< 0.01& P< 0.03 respectively), and their level were significantly higher in smoker males infected with H.
pylori (P<0.001).
Conclusions: This study showed that the rate of H.
pylori infection among smoker is higher than that of non-smokers and cigarette smoking was an important risk factor for H.
pylori infection as well, smokers have higher levels of IL-4 and IL-8 than never-smokers.
American Psychological Association (APA)
Said, Chiman Hamid. 2021. Effect of helicobacter pylori infection on interleukin-4 and interleukin-8 levels in smoker males. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 29, no. 1, pp.97-106.
https://search.emarefa.net/detail/BIM-1383678
Modern Language Association (MLA)
Said, Chiman Hamid. Effect of helicobacter pylori infection on interleukin-4 and interleukin-8 levels in smoker males. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 29, no. 1 (Jan. / Apr. 2021), pp.97-106.
https://search.emarefa.net/detail/BIM-1383678
American Medical Association (AMA)
Said, Chiman Hamid. Effect of helicobacter pylori infection on interleukin-4 and interleukin-8 levels in smoker males. Journal of Babylon University : Journal of Applied and Pure Sciences. 2021. Vol. 29, no. 1, pp.97-106.
https://search.emarefa.net/detail/BIM-1383678
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 105-106
Record ID
BIM-1383678