The new approach of hyaluronic binding assay in relevance to sperm activation by direct swim-up technique in infertile men with asthenozoospermia

Abstract EN

Asthenozoospermia is one of the main causes of infertility or diminished fertility in men , hyaluronic acid (HA) is a complex bioactive agent , which is fully represented in the female reproductive tract.

the oocyte of human being is enclosed by (HA), which acts as a physical selector of spermatozoa.

human sperm cells that assay (HBA score%) is an important diagnostic tool for suspicious male infertility in the analysis of semen.

in a matter of minutes , provides the mature binding spermatozoa in the sample .direct swim-up technique is the oldest and most frequently used activation technique.

to assess the sperm parameters and the percentage of binding spermatozoa to ha pre-and post-in vitro sperm activation for asthenozoospermic men.

Twenty-two asthenozoospermia men were collaborate in this study.

assessmet of sperm parameters and HBA score% pre- and post - direct swim up technique and the results were statistically analyzed.

significant increment (p-value<0.05) was noticed within progressive motility, morphology of spermatozoa and a significant improvement in (HBA- Score) post-activation.