Liver molecular-biochemical markers in viral hepatitis B patients

Joint Authors

Khidr, Lana Basil
Sabir, Fakhir Najm K.

Source

ZANCO Journal of Pure and Applied Sciences

Issue

Vol. 33, Issue 3 (30 Jun. 2021), pp.85-97, 13 p.

Publisher

Salahaddin University-Erbil Department of Scientific Publications

Publication Date

2021-06-30

Country of Publication

Iraq

No. of Pages

13

Main Subjects

Agriculture

Abstract EN

The prevalence of liver disease has led to its emergence as a major challenge.

This challenge is also attributed to factors such as the challenging diagnosis, complexity of pathogenesis, and the absence of established therapies.

When Hepatitis B virus (HBV) infections occurs in patients that do not have detectable hepatitis B surface antigen (HBsAg), it is referred to as occult infections.

Despite the fact that these kinds of infections have been found in patients with chronic hepatitis C liver disease, there is still no evidence on their clinical implication and prevalence.

HBV is a small partial deoxy ribonucleic acid (DNA) virus with like retroviruses.

The virus falls under the group of Hepadnavirus infections and family of orthohepadna virus.

About 66% of patients with acute HBV infection have an asymptomatic, mild, and sub-clinical illness that typically goes undetected.

Thus, in this work, hematological parameters were used in detecting the virus, and the results of the hematological parameters revealed significant changes in white blood cell (WBC), lymphocyte and platelet area under curve (AUC) (0.95), (0.66), and (0.82).

The mean values for ALT and ALP in HBV-positive patients increased significantly as compared to the control.

Similarly, there was no significant difference between the AUC, CI for HBV-positivity for ALT 0.91, (0.8485-0.9854) and ALP 0.89 (0.8123- 0.9633).

This study revealed a significant positive correlation between ALP level and ALT and each lymphocyte, granulocyte and WBCs.

Thus, each of them may be considered as major factors of development of HBV level.

American Psychological Association (APA)

Khidr, Lana Basil& Sabir, Fakhir Najm K.. 2021. Liver molecular-biochemical markers in viral hepatitis B patients. ZANCO Journal of Pure and Applied Sciences،Vol. 33, no. 3, pp.85-97.
https://search.emarefa.net/detail/BIM-1387335

Modern Language Association (MLA)

Khidr, Lana Basil& Sabir, Fakhir Najm K.. Liver molecular-biochemical markers in viral hepatitis B patients. ZANCO Journal of Pure and Applied Sciences Vol. 33, no. 3 (2021), pp.85-97.
https://search.emarefa.net/detail/BIM-1387335

American Medical Association (AMA)

Khidr, Lana Basil& Sabir, Fakhir Najm K.. Liver molecular-biochemical markers in viral hepatitis B patients. ZANCO Journal of Pure and Applied Sciences. 2021. Vol. 33, no. 3, pp.85-97.
https://search.emarefa.net/detail/BIM-1387335

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 96-97

Record ID

BIM-1387335