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The main bioactive constituents of traditional kurdish plant Achellia oligocephala DC : their antiproliferative and antioxidant activities
Author
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 32, Issue 5 (31 Oct. 2020), pp.106-117, 12 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2020-10-31
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Abstract EN
Achellia oligocephala DC.
, which grows in the mountains, is very popular as wound healing and gastrointestinal complaints.
This research article reports the first study of the phytochemical investigation and biological properties of bioactive secondary metabolites from the traditional Kurdish plant Achellia oligocephala.
(+) - Luteolin-6-C-glucoside (AO1) and Lupeol (AO2) were isolated from aerial parts for the first time from this plant.
The antiproliferative activity was measured against three human tumour cell lines, MCF7, SkBr3, and BG-1 cancer cells by using the MTT assay.
Notably, the (+) - Luteolin-6-C-glucoside showed significant antiproliferative activity against MCF7 cancer cell line, IC50 value (10 µg/mL).
The antioxidant activity of AO1 and AO2 were evaluated on total antioxidant capacity (TOAC) test.
Interestingly, its showed a remarkable antioxidant activity compared to standard antioxidant.
This study confirms that (+) - Luteolin-6-C-glucoside can be considered a natural anticancer and antioxidant compound.
American Psychological Association (APA)
Amin, Hawraz Ibrahim Muhammad. 2020. The main bioactive constituents of traditional kurdish plant Achellia oligocephala DC : their antiproliferative and antioxidant activities. ZANCO Journal of Pure and Applied Sciences،Vol. 32, no. 5, pp.106-117.
https://search.emarefa.net/detail/BIM-1388272
Modern Language Association (MLA)
Amin, Hawraz Ibrahim Muhammad. The main bioactive constituents of traditional kurdish plant Achellia oligocephala DC : their antiproliferative and antioxidant activities. ZANCO Journal of Pure and Applied Sciences Vol. 32, no. 5 (2020), pp.106-117.
https://search.emarefa.net/detail/BIM-1388272
American Medical Association (AMA)
Amin, Hawraz Ibrahim Muhammad. The main bioactive constituents of traditional kurdish plant Achellia oligocephala DC : their antiproliferative and antioxidant activities. ZANCO Journal of Pure and Applied Sciences. 2020. Vol. 32, no. 5, pp.106-117.
https://search.emarefa.net/detail/BIM-1388272
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 116-117
Record ID
BIM-1388272