Evaluating of some serum biochemical parameters in thyroid dysfunction women in Kalar’s General Hospital

Joint Authors

Ali, Zayn Abd Allah
Said, Hero Helal Muhammad

Source

ZANCO Journal of Pure and Applied Sciences

Publisher

Salahaddin University-Erbil Department of Scientific Publications

Publication Date

2017-08-31

Country of Publication

Iraq

No. of Pages

11

Main Subjects

Chemistry

English Abstract

Thyroid hormones are the body’s primary regular of normal development of organs.

High and low levels of Thyroid hormones alter the balance of metabolism of oxygen in human cells and stimulate the over production of free radicals which associated with many biochemical abnormalities.

The study conducted on (40) newly diagnosed hypothyroidism females (Group 1), (40) treated hypothyroidism with L-Thyroxin for more than six months (Group 2), (40) newly diagnosed hyperthyroidism females (Group 3), and (40) treated hyperthyroidism with carbamizole for more than six months (Group 4).

The patient’s biochemical parameters were compared with that for (40) apparently healthy control.

Fasting blood samples were taken from all participant and analyzed for peroxynitrite, ceruloplasimin (CP), vitamins C (vit.

C), Albumin (Alb), and glutathione (GSH).

The levels of peroxynitrite increased significantly in all patients, pre and post treatment compared to healthy control.

Ceruloplasimin, in all patients, pre and post treatment, showed no significant differences from that of control group.

Albumin was found to be compatible with control group apart from untreated hypothyroidism (Group 1) who showed significantly lower value.

The level of vitamin C showed significantly low levels pretreatment for both patient groups.

The level showed no significant differences from control after treatment, while, serum Glutathione concentration showed a significant decrease in all groups in comparison with the control.

Data Type

Conference Papers

Record ID

BIM-1388960

• APA
• MLA
• AMA