Role of oral versus long-acting, second-generation medications for enhancing adherence and preventing rehospitalization in patients with schizophrenia
Other Title(s)
مقارنة مضادات الذهان الفموية اليومية بمضادات الذهان طويلة المفعول بمرضي الفصام لتحسين الالتزام بالعلاج و تقليل الحاجة للتنويم بالمستشفى
Joint Authors
Sayyid, Haydi Hasan
al-Sayyid, Muna
Source
The Arab Journal of Psychiatry
Issue
Vol. 32, Issue 2 (30 Nov. 2021), pp.154-161, 8 p.
Publisher
The Arab Federation of Psychiatrists
Publication Date
2021-11-30
Country of Publication
Jordan
No. of Pages
8
Main Subjects
Abstract EN
As psychopathology and social functioning can worsen with repeated psychotic episodes, relapse prevention is critical in schizophrenia and because non-adherence decreases response to pharmacotherapy, the use of long-acting, injectable (LAI) antipsychotics is considered an important treatment option.
Aims : the current study aims to assess the experience of adherence and rehospitalization in patients with schizophrenia who receive second-generation, oral or long-acting injectable antipsychotics following hospital discharge.
Method : a prospective comparative study was carried out from April 2018 to march 2019 in an outpatient psychiatry clinic in Ismailia, Egypt.
in total, 70 patients with a diagnosis of schizophrenia were recruited ; ages ranged from 18 to 40 years; and all were allocated to one of two groups.
group a consisted of 35 patients maintained on oral, second-generation antipsychotic (SGA).
group b consisted of 35 patients maintained on long-acting injection second generation antipsychotic.
patients were followed up for one year to assess adherence, discontinuation and rehospitalization.
results : patients on long-acting, second generation antipsychotic injection (LAAI) were more adherent and required fewer rehospitalizations than those on oral, second-generation antipsychotics (OAP).
conclusion : long-acting antipsychotic injections may have a role in enhancing medication adherence for patients with a diagnosis of schizophrenia and may also decrease the need for hospitalization.
American Psychological Association (APA)
al-Sayyid, Muna& Sayyid, Haydi Hasan. 2021. Role of oral versus long-acting, second-generation medications for enhancing adherence and preventing rehospitalization in patients with schizophrenia. The Arab Journal of Psychiatry،Vol. 32, no. 2, pp.154-161.
https://search.emarefa.net/detail/BIM-1410091
Modern Language Association (MLA)
al-Sayyid, Muna& Sayyid, Haydi Hasan. Role of oral versus long-acting, second-generation medications for enhancing adherence and preventing rehospitalization in patients with schizophrenia. The Arab Journal of Psychiatry Vol. 32, no. 2 (Nov. 2021), pp.154-161.
https://search.emarefa.net/detail/BIM-1410091
American Medical Association (AMA)
al-Sayyid, Muna& Sayyid, Haydi Hasan. Role of oral versus long-acting, second-generation medications for enhancing adherence and preventing rehospitalization in patients with schizophrenia. The Arab Journal of Psychiatry. 2021. Vol. 32, no. 2, pp.154-161.
https://search.emarefa.net/detail/BIM-1410091
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 159-160
Record ID
BIM-1410091