Chemical characteristics and targeted encapsulated Cordia myxa fruits extracts nanoparticles for antioxidant and cytotoxicity potentials

Joint Authors

al-Ghurab, Ahmad Hasan
Najib, Ibrahim Ahmad
Musa, Arafah
Mustafa, Ihab Muhammad
Ghunaym, Muhammad Mahmud
Khazim, Muhammad Abd al-Wahhab Abd al-Jawad
al-Misri, Khalid Faruq
Faruq, Amr
Mahmud, Khalid F.
Sharif, S. M.

Source

Saudi Journal of Biological Sciences

Issue

Vol. 28, Issue 9 (30 Sep. 2021), pp.5349-5358, 10 p.

Publisher

Saudi Biological Society

Publication Date

2021-09-30

Country of Publication

Saudi Arabia

No. of Pages

10

Main Subjects

Biology

Abstract EN

A promising Cordia myxa fruit (CMF) extract targets an additional incorporation in functional foods.

It retains appropriate health welfares owing to its antioxidant properties with limited incorporation in food matrices due its hydrophobicity.

Therefore, CMF extract micro- and nanocapsulation was performed to protect and facilitate consistency of produced hydrophobic foods matrices.

Furthermore, to determine its phytochemicals, antioxidant, and cytotoxic effects by applying analytical HPLC, FRAP and SRB assay, respectively.

HPLC analysis of the tested extracts revealed the presence of, 25.59 ± 1.78 mg catechin/g, 69.68 ± 4.20 mg quercetin/g, and 112.72 ± 8.38 mg gallic acid/g extract.

The CMF extract displayed a potent DPPH radicals' scavenger and FRAP high reduction capability in a dose-dependent manner.

The potent pharmacological activities of CMF extract may be ascribed to high concentration of polyphenolics including flavonoids which strongly reported to possess an antitumor and antioxidant activities.

To confirm the efficient CMF incorporation in micro- and nanosystems and their thermal stabilities to withstand the high temperatures applied during some food processing.

DSC of the apparent melt of non-capsulated CMF and encapsulated forms (MCMF and NCMF) in sodium alginate gel and beads was studied.

Results showed that melting point of CMF extract (86.17 °C) indicating its inability whereas the MCMF and NCMF melting points (226.45 and 383.87 °C, respectively) demonstrating the capability of expending alginate - packaging material to shield the vital active compounds of C.

myxa fruit to be applied in different targeted delivery products especially that disclosed to high thermal treatments.

American Psychological Association (APA)

al-Misri, Khalid Faruq& Faruq, Amr& Mahmud, Khalid F.& al-Ghurab, Ahmad Hasan& Sharif, S. M.& Musa, Arafah…[et al.]. 2021. Chemical characteristics and targeted encapsulated Cordia myxa fruits extracts nanoparticles for antioxidant and cytotoxicity potentials. Saudi Journal of Biological Sciences،Vol. 28, no. 9, pp.5349-5358.
https://search.emarefa.net/detail/BIM-1411392

Modern Language Association (MLA)

al-Misri, Khalid Faruq…[et al.]. Chemical characteristics and targeted encapsulated Cordia myxa fruits extracts nanoparticles for antioxidant and cytotoxicity potentials. Saudi Journal of Biological Sciences Vol. 28, no. 9 (2021), pp.5349-5358.
https://search.emarefa.net/detail/BIM-1411392

American Medical Association (AMA)

al-Misri, Khalid Faruq& Faruq, Amr& Mahmud, Khalid F.& al-Ghurab, Ahmad Hasan& Sharif, S. M.& Musa, Arafah…[et al.]. Chemical characteristics and targeted encapsulated Cordia myxa fruits extracts nanoparticles for antioxidant and cytotoxicity potentials. Saudi Journal of Biological Sciences. 2021. Vol. 28, no. 9, pp.5349-5358.
https://search.emarefa.net/detail/BIM-1411392

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 5357-5358

Record ID

BIM-1411392