Systematic review on medicinal plants used for the treatment of Giardia infection
Joint Authors
al-Numasi, Sultan
al-Awsi, Ghayda Rahim Latif
Raziani, Yusra
al-Balawi, Aishah E.
Niazi, Masumah
Mahmudvand, Husayn
al-Anzi, Abd Allah Bin Dari
Source
Saudi Journal of Biological Sciences
Issue
Vol. 28, Issue 9 (30 Sep. 2021), pp.5391-5402, 12 p.
Publisher
Publication Date
2021-09-30
Country of Publication
Saudi Arabia
No. of Pages
12
Main Subjects
Abstract EN
Background: However, broad adoption of herbal remedies for giardiasis is at present hampered by uncertain findings of investigation not always sufficiently powered.
This study was aimed at systematically reviewing the existing literature in herbal medicines to treat giardiasis.
Methods: This review was carried out 06- PRISMA guideline and registered in the CAMARADES-NC3Rs Preclinical Systematic Review and Meta-Analysis Facility (SyRF) database.
The search was performed in five databases which are Scopus, PubMed, Web of Science, EMBASE, and Google Scholar without time limitation for all published articles (in vitro, in vivo, and clinical studies).
The searched words and terms were: "Giardia", "giardiasis", "extract", "essential oil", "herbal medicines", "anti-Giardia", "In vitro", "In vivo", "clinical trial" etc.
Results: Out of 1585 papers, 40 papers including 28 in vitro (70.0%), 7 in vivo (17.5%), 2 in vitro/ in vivo (5.0%), and 3 clinical trials (7.5%) up to 2020, met the inclusion criteria for discussion in this systematic review.
The most widely used medicinal plants against Giardia infection belong to the family Lamiaceae (30.0%) followed by Asteraceae (13.5%), Apiaceae (10.5%).
The most common parts used in the studies were aerial parts (45.0%) followed by leaves (27.4%) and seeds (7.5%).
The aqueous extract (30.0%), essential oil (25.4%) and hydroalcholic and methanolic (10.5%) were considered as the desired approaches of herbal extraction, respectively.
Conclusion: The current review showed that the plant-based anti-Giardia agents are very promising as an alternative and complementary resource for treating giardiasis since had low significant toxicity.
However, more studies are required to elucidate this conclusion, especially in clinical systems.
American Psychological Association (APA)
al-Numasi, Sultan& al-Awsi, Ghayda Rahim Latif& Raziani, Yusra& al-Balawi, Aishah E.& al-Anzi, Abd Allah Bin Dari& Niazi, Masumah…[et al.]. 2021. Systematic review on medicinal plants used for the treatment of Giardia infection. Saudi Journal of Biological Sciences،Vol. 28, no. 9, pp.5391-5402.
https://search.emarefa.net/detail/BIM-1411436
Modern Language Association (MLA)
al-Numasi, Sultan…[et al.]. Systematic review on medicinal plants used for the treatment of Giardia infection. Saudi Journal of Biological Sciences Vol. 28, no. 9 (2021), pp.5391-5402.
https://search.emarefa.net/detail/BIM-1411436
American Medical Association (AMA)
al-Numasi, Sultan& al-Awsi, Ghayda Rahim Latif& Raziani, Yusra& al-Balawi, Aishah E.& al-Anzi, Abd Allah Bin Dari& Niazi, Masumah…[et al.]. Systematic review on medicinal plants used for the treatment of Giardia infection. Saudi Journal of Biological Sciences. 2021. Vol. 28, no. 9, pp.5391-5402.
https://search.emarefa.net/detail/BIM-1411436
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 5401-5402
Record ID
BIM-1411436