Effect of low-fat diet in the presence of artichoke leaves on obese rats suffering from damage in the liver
Other Title(s)
تأثير النظام الغداني منخفض الدهن المحتوي على أوراق الخرشوف على الفران البدينة المصابة بتحطم في الكبد
Joint Authors
Abd al-Khaliq, Dalia Muhammad Talat
Shihatah, Aminah Mahmud Abd al-Ghani
Ibrahim, Khalid Ramadan
Source
The Scientific Journal of Specific Education and Applied Sciences
Issue
Vol. 5, Issue 13 (31 Jul. 2022), pp.32-69, 38 p.
Publisher
Fayoum University Faculty of Specific Education
Publication Date
2022-07-31
Country of Publication
Egypt
No. of Pages
38
Main Subjects
Topics
- Liver
- Diseases
- Penal functions
- Medical examinations
- Feeds
- Regime alimentaire
- Carbon tetrachloride
- Weight gain
Abstract EN
This study was performed to examine the impact of three levels of artichoke leaves on obese rats suffering from liver damage triggered by carbon tetrachloride (CCl4).
This study was designed as follows: Forty-eight male albino rats weighting (200±10g) were utilized in this research.
The rats were categorized into two main groups; Group 1 (the control negative group), included six rats that received a basal diet; Group 2 included 42 rats that received a high-fat diet (HFD) for six weeks to induce obesity.
Subsequently, animals in Group 2 were treated with CC14 subcutaneous injection (for 14 days) to induce liver damage.
Alanine amino transaminase (ALT), weight gain, aspartate amino transaminase (AST), as well as lipid profile were assessed in both groups after this period to ensure obesity as well as liver damage induction.
The animals in Group 2 were subdivided into seven subgroups: Subgroup (1) received HFD and was utilized as positive controls.
Subgroups (2, 3, and 4) received HFD containing (25g, 50g, and 100g dried Artichoke leaves/kg diet), respectively.
Subgroups (5, 6, and 7) received a low-fat diet LFD containing (25g, 50g, and 100g dried Artichoke leaves/kg diet), respectively.
By the end of the trial, feed intake and the proportion of gaining bodyweight were estimated.
In addition, serum glucose, lipid profile, liver enzymes, and kidney functions were determined in all groups.
The obtained results revealed that all groups treated demonstrated substantial improvement in these indices.
Treatment of obese groups suffering from damage in the liver with a low-fat diet containing the three levels from artichoke leaves, induced a substantial improvement in these indices compared to the obese groups, which were suffering from liver damage and treated with an HFD containing the same levels from the artichoke.
Based on these outcomes, we may infer that Artichoke leaves may improve the adverse effects of obesity and liver disease.
American Psychological Association (APA)
Shihatah, Aminah Mahmud Abd al-Ghani& Abd al-Khaliq, Dalia Muhammad Talat& Ibrahim, Khalid Ramadan. 2022. Effect of low-fat diet in the presence of artichoke leaves on obese rats suffering from damage in the liver. The Scientific Journal of Specific Education and Applied Sciences،Vol. 5, no. 13, pp.32-69.
https://search.emarefa.net/detail/BIM-1412929
Modern Language Association (MLA)
Abd al-Khaliq, Dalia Muhammad Talat…[et al.]. Effect of low-fat diet in the presence of artichoke leaves on obese rats suffering from damage in the liver. The Scientific Journal of Specific Education and Applied Sciences Vol. 5, no. 13 (Jul. 2022), pp.32-69.
https://search.emarefa.net/detail/BIM-1412929
American Medical Association (AMA)
Shihatah, Aminah Mahmud Abd al-Ghani& Abd al-Khaliq, Dalia Muhammad Talat& Ibrahim, Khalid Ramadan. Effect of low-fat diet in the presence of artichoke leaves on obese rats suffering from damage in the liver. The Scientific Journal of Specific Education and Applied Sciences. 2022. Vol. 5, no. 13, pp.32-69.
https://search.emarefa.net/detail/BIM-1412929
Data Type
Journal Articles
Language
English
Notes
-
Record ID
BIM-1412929