Theoretical and spectroscopic studies of SN donor thiosemicarbazone ligand and its Pt(II) complex
Other Title(s)
دراسة طيفية و حسابية لمرتبط SN-ثايوسيميكاربازون المعطي و معقده مع البلاتين (II)
Joint Authors
Ali, Aminah Qasim Ali
Hassunah, Bu Bakr Miftah
Ahmidah, Khadijah Abd al-Salam
al-Sharif, Abd al-Salam Amhammad Muhammad
Source
Journal of Pure and Applied Sciences
Issue
Vol. 20, Issue 1 (31 Mar. 2021), pp.113-117, 5 p.
Publisher
Publication Date
2021-03-31
Country of Publication
Libya
No. of Pages
5
Main Subjects
Abstract EN
Sulphur-nitrogen(SN) donor thiosemicarbazone ligand [(Z)-N-ethyl-2-(5-methyl-2-oxoindolin-3-ylidene)hydrazinecarbothioamide] and its Pt(II) complex were synthesized by condensation method.
The compounds were structurally characterized by elemental analysis CHNS, FT-IR, and NMR analysis.
The elemental analyses data for the compounds were in good agreement with the theoretical values.
The melting point of the complex was higher than the ligand, as expected.
The FT-IR spectral data reflect a bidentate bonding of thiosemicarbazone ligand to Pt(II) ion through thioketo sulfur and azomethine nitrogen.
The docking results (theoretical results) of these compounds show that the binding energy between DNA and Pt(II) complex was found to be less than that of the Schiff base ligand (L) in the sense that it has higher stability at various stages and angles.
The strength of docking between DNA and Pt(II) complex was also found to be that stronger than the Schiff base ligand (L).
American Psychological Association (APA)
Ali, Aminah Qasim Ali& Hassunah, Bu Bakr Miftah& Ahmidah, Khadijah Abd al-Salam& al-Sharif, Abd al-Salam Amhammad Muhammad. 2021. Theoretical and spectroscopic studies of SN donor thiosemicarbazone ligand and its Pt(II) complex. Journal of Pure and Applied Sciences،Vol. 20, no. 1, pp.113-117.
https://search.emarefa.net/detail/BIM-1419223
Modern Language Association (MLA)
Ali, Aminah Qasim Ali…[et al.]. Theoretical and spectroscopic studies of SN donor thiosemicarbazone ligand and its Pt(II) complex. Journal of Pure and Applied Sciences Vol. 20, no. 1 (Mar. 2021), pp.113-117.
https://search.emarefa.net/detail/BIM-1419223
American Medical Association (AMA)
Ali, Aminah Qasim Ali& Hassunah, Bu Bakr Miftah& Ahmidah, Khadijah Abd al-Salam& al-Sharif, Abd al-Salam Amhammad Muhammad. Theoretical and spectroscopic studies of SN donor thiosemicarbazone ligand and its Pt(II) complex. Journal of Pure and Applied Sciences. 2021. Vol. 20, no. 1, pp.113-117.
https://search.emarefa.net/detail/BIM-1419223
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-1419223