Study of inclusion complex between metoprolol tartrate and methyl beta Cyclodextrine
Joint Authors
Yunus, Ula Mahmud
Um Ali, Fida
al-Assaf, Zayd
Source
Arab Journal for Pharmaceutical Sciences
Issue
Vol. 6, Issue 1 (31 Jul. 2019)8 p.
Publisher
Publication Date
2019-07-31
Country of Publication
Syria
No. of Pages
8
Main Subjects
Abstract EN
The inclusion complex between Metoprolol tartrate and methyl P cyclodextrin (MpCD) has been formed then investigated using 1H-nuclear magnetic resonance (NMR) in dimethyl sulphoxide (DMSO-d6) as a solvent.
UV spectrometry indicated that a complex with 1:1 stoichiometry is predominant in the solution.
1H NMR chemical shift displacements between complexed and free metoprolol tartrate were significant .
The data suggested that the methoxyethyl moiety and aromatic region of metoprolol tartarte are deeply inserted in cyclodextrine cavity, while the residual side chain of metoprolol tartrate stayed outside of the cavity above or below the torus ring of MpCD.
American Psychological Association (APA)
Yunus, Ula Mahmud& Um Ali, Fida& al-Assaf, Zayd. 2019. Study of inclusion complex between metoprolol tartrate and methyl beta Cyclodextrine. Arab Journal for Pharmaceutical Sciences،Vol. 6, no. 1.
https://search.emarefa.net/detail/BIM-1424445
Modern Language Association (MLA)
Yunus, Ula Mahmud…[et al.]. Study of inclusion complex between metoprolol tartrate and methyl beta Cyclodextrine. Arab Journal for Pharmaceutical Sciences Vol. 6, no. 1 (Jul. 2019).
https://search.emarefa.net/detail/BIM-1424445
American Medical Association (AMA)
Yunus, Ula Mahmud& Um Ali, Fida& al-Assaf, Zayd. Study of inclusion complex between metoprolol tartrate and methyl beta Cyclodextrine. Arab Journal for Pharmaceutical Sciences. 2019. Vol. 6, no. 1.
https://search.emarefa.net/detail/BIM-1424445
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1424445
