Central venous line bloodstream infections during hematopoietic stem cell transplantation for primary immunodeficiency disorders
Joint Authors
al-Khawlidah, Mahir
al-Zayyud, Raid
Zayyud, Ali
al-Nawbani, Muhammad
al-Adayilah, Bushra
Source
Journal of the Royal Medical Services
Issue
Vol. 29, Issue 1 (30 Apr. 2022), pp.6-12, 7 p.
Publisher
The Royal Medical Services Jordan Armed Forces
Publication Date
2022-04-30
Country of Publication
Jordan
No. of Pages
7
Main Subjects
Abstract EN
Background : a central venous line (CVL) is a large-pore intravascular catheter placed into a large vein and dedicated for infusion, withdrawal of blood, and administration of chemotherapy, as in hematopoietic stem cell transplantation (HSCT) patients.
one of the serious complications of CVL is central-line–associated bloodstream infection (CLABSI).
we described CLABSI incidence in primary immunodeficiency disorder (PID) patients who underwent HSCT at queen Rania children’s hospital in a retrospective analysis.
methods : a retrospective analysis of 58 PID patients who were admitted for HSCT from 2014 through 2019 at the bone marrow transplant unit (BMT); positive CLABSI isolates were analysed.
results :out of 58 total patients who underwent HSCT for PID over the study period, 28 (48.3%) were positive for CLABSI.
among those CLABSI-positive patients, 52 CLABSI episodes were isolated over the study period, which were categorized into gram-positive bacteria in 28 episodes (58%), gram-negative bacteria in 19 (36.5%) episodes, and fungi in five (9.5%) episodes.
the most frequently isolated pathogens were staphylococcus epidermises, klebsiella spp., methicillin-resistant staphylococcus aureus (MRSA), and enterococci spp., in 17%, 11.5%, 7.7, and 7.7%, respectively.
conclusions : primary immunodeficiency disorder (PID) patients who underwent HSCT had a different order of CLABSI causative pathogens from what had been reported in paediatric oncological disease and HSCT patients.
American Psychological Association (APA)
al-Khawlidah, Mahir& al-Zayyud, Raid& Zayyud, Ali& al-Nawbani, Muhammad& al-Adayilah, Bushra. 2022. Central venous line bloodstream infections during hematopoietic stem cell transplantation for primary immunodeficiency disorders. Journal of the Royal Medical Services،Vol. 29, no. 1, pp.6-12.
https://search.emarefa.net/detail/BIM-1435329
Modern Language Association (MLA)
al-Khawlidah, Mahir…[et al.]. Central venous line bloodstream infections during hematopoietic stem cell transplantation for primary immunodeficiency disorders. Journal of the Royal Medical Services Vol. 29, no. 1 (Apr. 2022), pp.6-12.
https://search.emarefa.net/detail/BIM-1435329
American Medical Association (AMA)
al-Khawlidah, Mahir& al-Zayyud, Raid& Zayyud, Ali& al-Nawbani, Muhammad& al-Adayilah, Bushra. Central venous line bloodstream infections during hematopoietic stem cell transplantation for primary immunodeficiency disorders. Journal of the Royal Medical Services. 2022. Vol. 29, no. 1, pp.6-12.
https://search.emarefa.net/detail/BIM-1435329
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 12
Record ID
BIM-1435329