Body mass index (BMI)‎ as risk factor for developing hypogonadism among Sudanese patient with chronic kidney disease

Abstract EN

Background: CKD, beside its heterogeneous clinical disorders, it is the general term used for describing an irreversible loss of kidney function, that develops due to multifactorial etiology over a period of few years, with prevalence rate between 11%-13% globally and 5%-7% locally.

So the aim of this study was designed to investigate the association of the serum testosterone in patient with CKD.

Methods: The study was conducted at the Military Hospital, Police Hospital and the Kidney Transplantation Association.

A case-control study was completed within the six months; i.

e.

from November 2017 to April 2018.

The study was carried out on a total sample of 80 subjects, including 40 CKD patients as case and 40 healthy individuals as control group.

The serum testosterone was estimated using ELISA technique, and the data was analyzed statistically using the Microsoft SPSS® program version 21.

Results: this study revealed that testosterone level had decreased significantly in CKD patient in comparison to the control group, (p-value 0.041).

Furthermore, BMI also had a significant impact on testosterone level, (p-value 0.013).

Conclusion: This study has showed that, the patients had developed hypogonadism as a result of CKD, together with the increasing BMI.