Phytochemical and antibacterial screening of aqueous and hexane extracts of acacia nilotica fruit against bacterial species from human isolates

Abstract EN

Aqueous and hexane extracts of Acacia nilotica fruit were used to evaluate the antibacterial activities against seven human isolates collected from Khartoum National Laboratory.

Results indicated the presence of Salmonella typhi, Shigella flexnri, Klelsiella pneuomoniae, Escherichia coli, Pseudomonas aernginosa, Proteus mirabilis and Vibrio cholerae.

Results indicated that the aqueous extract and hexane (hot and cold) extract of Acacia nilotica inhibited the growth of various species of Gram-negative and Grampositive bacteria, and the aqueous extract which prepared by soaking was more effective against the bacteria than the hot hexane extract.Wherease the extraction method affect on the efficiency extract.

Also the phytochemical analysis results revealed the presence of tannins, co-anthraquinones, alkaloids, flavonoids, saponin, terpenoids and glycosides, the objectives of the study were to evaluate the phytochemical constituents of the aqueous and hexane extracts of Acacia nilotica fruit, and to assess the antibacterial activity of these constituents.

The experimental and analytical method was used.

The importance of the study was derived from that many diseases were spread among inhabitants in rural areas, and the resistance of the bacteria to certain antibiotics.

This inforced scientists to look for other alternative, that the using of the aromatic and medicinal plants.

As the components of these plants were safe, effective and cheap.