Prostate specific antigen protein level as biomarker in breast carcinoma patients at oncology centre in Sebha city-Libya

Abstract EN

Breast carcinoma is one of the most common types of carcinomas worldwide in female women of all ages according to world health organization.

The current study was aimed to evaluate whether the Prostate Specific Antigen (PSA) protein level could serve as a biomarker for breast carcinoma.

In this study, Immunoeznymometric assay was performed to evaluate PSA protein level of 60 women's; 40 women's with breast carcinoma and 20 healthy women's (without carcinoma) was used as control group.

The mean age was 46.3 years; age range (28 to 64 years).

The Mean PSA protein level was 0.324 ng/ml, SD was 0.387, P-value was 0.330 > 0.05.

This study is the first study to report no high expression of PSA protein was observed in Libyan women's who has breast carcinoma, and there was no association between PSA proteins with breast carcinoma.

This indicates that the PSA protein has no important role as an indicator for breast cancers patients from women's and cannot be biomarker for breast carcinoma.