Pre-emptive analgesic efficacy of intravenous diclofenac versus paracetamol in orthopedic surgery
Joint Authors
Jan, Munir
Singh, Gaurav
Zarfishan, Anna
Kumar, Updesh
Gupta, Raghav
Source
Issue
Vol. 43, Issue 1 (31 Mar. 2021), pp.354-356, 3 p.
Publisher
King Hamad University Hospital
Publication Date
2021-03-31
Country of Publication
Bahrain
No. of Pages
3
Main Subjects
Abstract EN
Background: Different treatment modalities have been proposed to relieve pain after orthopedic surgeries, however, despite significant advances in pain management, it is still inadequately relieved.
Objective: To evaluate the pre-emptive analgesic efficacy of diclofenac and paracetamol in patients undergoing orthopedic surgery of the upper limbs.
Design: A Prospective Randomized, Double-Blind, Controlled Study.
Setting: St.
Stephen’s Hospital, New Delhi, India.
Method: This prospective randomized, double-blind, controlled study was performed on 100 patients of the American Society of Anesthesiologists (ASA) physical status classes 1 and 2 with an age group of 18-65 years of either sex undergoing upper limb orthopedic surgery.
Group P (paracetamol) patients have been given 1g paracetamol intravenously 30 minutes before surgery.
Group D (diclofenac) have been given intravenous 75 mg diclofenac sodium (in 100 ml 0.9% saline) 30 minutes before surgery.
Result: Personal and clinical characteristics were comparable between the two groups.
The mean time between extubation and the need for the first analgesic dose was 75.46±15.72 minutes in Group P and 137.12±12.5 minutes for Group D (p-value =0.002).
The number of IV fentanyl (1 mcg kg-1) doses following extubation in the first 6 hours was 1.83±0.21in Group P and 1.20±0.24 for Group D (p-value =0.03).
Nausea/vomiting was reported 2 (6.67%) patients in Group D, and 3 (10%) in Group P.
Conclusion: Pre-emptive administration of diclofenac and paracetamol is cost-effective, and safe method of providing postoperative analgesia for patients undergoing orthopedic surgery of the upper limbs.
American Psychological Association (APA)
Jan, Munir& Singh, Gaurav& Zarfishan, Anna& Gupta, Raghav& Kumar, Updesh. 2021. Pre-emptive analgesic efficacy of intravenous diclofenac versus paracetamol in orthopedic surgery. Bahrain Medical Bulletin،Vol. 43, no. 1, pp.354-356.
https://search.emarefa.net/detail/BIM-1440178
Modern Language Association (MLA)
Jan, Munir…[et al.]. Pre-emptive analgesic efficacy of intravenous diclofenac versus paracetamol in orthopedic surgery. Bahrain Medical Bulletin Vol. 43, no. 1 (Mar. 2021), pp.354-356.
https://search.emarefa.net/detail/BIM-1440178
American Medical Association (AMA)
Jan, Munir& Singh, Gaurav& Zarfishan, Anna& Gupta, Raghav& Kumar, Updesh. Pre-emptive analgesic efficacy of intravenous diclofenac versus paracetamol in orthopedic surgery. Bahrain Medical Bulletin. 2021. Vol. 43, no. 1, pp.354-356.
https://search.emarefa.net/detail/BIM-1440178
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 356
Record ID
BIM-1440178