Primary antiphospholipid syndrome : a hidden predisposing factor for retinal vein occlusion and choroidal neovascular membrane formation among young population
Joint Authors
al-Khalifah, Sad
al-Musa, Abd Allah
al-Danasuri, Rumysa Abd Allah
Ayyashi, Seemantini
Source
Journal of the Bahrain Medical Society
Issue
Vol. 33, Issue 3 (30 Sep. 2021), pp.30-35, 6 p.
Publisher
Publication Date
2021-09-30
Country of Publication
Bahrain
No. of Pages
6
Main Subjects
Abstract EN
Background and Objectives: Antiphospholipid syndrome can lead to variable systemic and ophthalmic manifestations.
The study aims to establish the relationship between retinal vein occlusion (RVO) or choroidal neovascular membrane (CNVM) with Antiphospholipid Syndrome (APS).
Methods: A multicentric prospective cross-sectional study was carried out in three major eye centers in Bahrain that included The Eye Infirmary, Bahrain Royal Hospital, and King Hamad University Hospital.
All young patients aging from 35 to 50 years, presenting with either RVO or CNVM and not known to have any underlying systemic disease were included in the study.
Antiphospholipid confirmatory tests and coagulation profiles were done for all patients.
Results: Total number of fourteen eyes of ten patients were enrolled in the study.
Six patients had RVO, three out of them had central retinal vein occlusion (CRVO) and three had branch retinal vein occlusion (BRVO).
Four patients had bilateral CNVM (total of 8 eyes).
All patients recorded high activated partial thromboplastin time (aPTT) readings, six out of ten patients were labeled as primary APS, four of them had positive anti-cardiolipin antibodies and the other two patients were positive for plasma lupus anticoagulant.
Conclusion: APS should be considered as an etiological factor in all cases of retinal vein occlusion and choroidal neovascular membrane affecting young otherwise healthy individuals.
In this study, 60% of patients who fit the inclusion criteria were labeled as primary APS patients.
Timely investigations and treatment in these cases can prevent major catastrophic thrombotic events which may involve any system or organ in the body.
American Psychological Association (APA)
al-Danasuri, Rumysa Abd Allah& al-Musa, Abd Allah& Ayyashi, Seemantini& al-Khalifah, Sad. 2021. Primary antiphospholipid syndrome : a hidden predisposing factor for retinal vein occlusion and choroidal neovascular membrane formation among young population. Journal of the Bahrain Medical Society،Vol. 33, no. 3, pp.30-35.
https://search.emarefa.net/detail/BIM-1440385
Modern Language Association (MLA)
al-Danasuri, Rumysa Abd Allah…[et al.]. Primary antiphospholipid syndrome : a hidden predisposing factor for retinal vein occlusion and choroidal neovascular membrane formation among young population. Journal of the Bahrain Medical Society Vol. 33, no. 3 (2021), pp.30-35.
https://search.emarefa.net/detail/BIM-1440385
American Medical Association (AMA)
al-Danasuri, Rumysa Abd Allah& al-Musa, Abd Allah& Ayyashi, Seemantini& al-Khalifah, Sad. Primary antiphospholipid syndrome : a hidden predisposing factor for retinal vein occlusion and choroidal neovascular membrane formation among young population. Journal of the Bahrain Medical Society. 2021. Vol. 33, no. 3, pp.30-35.
https://search.emarefa.net/detail/BIM-1440385
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 34-35
Record ID
BIM-1440385