Role of endoscopic ultrasound elastography in differential diagnosis of pancreatic solid masses

Abstract EN

Introduction: Endoscopic ultrasound (EUS) elastogra- phy is another technique that measures the stiffness of tissue and adds more diagnostic value to EUS.

Objective: This study aimed to assess the ability of qualitative and quantitative EUS elastography in differentiating malignant from benign solid pancreatic masses.

Methods: This 2-year cross-sectional study enrolled 80 patients with solid pancreatic masses in the department of endoscopy in Alassad University Hospital who underwent conventional and elasto- graphy-assisted EUS and then followed for pathology through EUS-guided or CT-guided biopsy or surgery.

Results: Qualitative elastography using a 5-point scoring system was able to recognize malignant pathology (obtained by EUS-guided biopsy, CT- guided biopsy, or surgery) with a sensitivity, specificity, and accuracy rates of 100%, 28.6%, and 81.3%, respectively.

A quantitative method using hue histogram had a sensitivity of 71.2%–86.4% and specificity of 71.4%–81% with the best accuracy for histogram mean ratio (area under the curve, 0.867).

Conclusion: EUS elastography is a simple and good alternative method in differentiating malignant from benign pancreatic solid masses.