Review article exploring the power and promise of in silico clinical trials with application in covid-19
Joint Authors
Fadl, Hibah Awad al-Karim Uthman
Abd al-Munim, bd al-Rahman H.
Khalil, Safinaz I.
Rewane, Ayesan
al-Bajer, Sahar G.
Source
Sudan Journal of Medical Sciences
Issue
Vol. 16, Issue 3 (30 Sep. 2021), pp.355-370, 16 p.
Publisher
Omdurman Islamic University Faculty of Medicine
Publication Date
2021-09-30
Country of Publication
Sudan
No. of Pages
16
Main Subjects
Abstract EN
Background: COVID-19 pandemic has dramatically engulfed the world causing catastrophic damage to human society.
Several therapeutic and vaccines have been suggested for the disease in the past months, with over 150 clinical trials currently running or under process.
Nevertheless, these trials are extremely expensive and require a long time, which presents the need for alternative cost-effective methods to tackle this urgent requirement for validated therapeutics and vaccines.
Bearing this in mind, here we assess the use of in silico clinical trials as a significant development in the field of clinical research, which holds the possibility to reduce the time and cost needed for clinical trials on COVID-19 and other diseases.
Methods: Using the PubMed database, we analyzed six relevant scientific articles regarding the possible application of in silico clinical trials in testing the therapeutic and investigational methods of managing different diseases.
Results: Successful use of in silico trials was observed in many of the reviewed evidence.
Conclusion: In silico clinical trials can be used in refining clinical trials for COVID-19 infection.
American Psychological Association (APA)
Abd al-Munim, bd al-Rahman H.& Khalil, Safinaz I.& Fadl, Hibah Awad al-Karim Uthman& Rewane, Ayesan& al-Bajer, Sahar G.. 2021. Review article exploring the power and promise of in silico clinical trials with application in covid-19. Sudan Journal of Medical Sciences،Vol. 16, no. 3, pp.355-370.
https://search.emarefa.net/detail/BIM-1442140
Modern Language Association (MLA)
Abd al-Munim, bd al-Rahman H.…[et al.]. Review article exploring the power and promise of in silico clinical trials with application in covid-19. Sudan Journal of Medical Sciences Vol. 16, no. 3 (2021), pp.355-370.
https://search.emarefa.net/detail/BIM-1442140
American Medical Association (AMA)
Abd al-Munim, bd al-Rahman H.& Khalil, Safinaz I.& Fadl, Hibah Awad al-Karim Uthman& Rewane, Ayesan& al-Bajer, Sahar G.. Review article exploring the power and promise of in silico clinical trials with application in covid-19. Sudan Journal of Medical Sciences. 2021. Vol. 16, no. 3, pp.355-370.
https://search.emarefa.net/detail/BIM-1442140
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 366-370
Record ID
BIM-1442140