Rams (Haloxylon Salicornicum)‎ powder and extract in diets of male albino rats to cope hyperglycemia

Abstract EN

This study aims to examine the effect of rams and levels for treatment of diabetic rats, powdered 5&7% and 5% extract were empared.

Twenty five adult male albino rats, weighing 150-160g were divided into two main groups and three groups, each with five rats.

The first main group: ( control negative ).

The second main group: 20 rats were injected with alloxan to induce diabetes, and then divided as following: Diabetic rats (non-treated, control positive), diabetic treated with a 5% rams herb powder, diabetic treated with a 7% rams herb powder and diabetic treated with oral rams herb alcohol extract of 30 ml / day).

At the end of experiment (4 weeks), the blood samples were collected after 12 hours fasting and serum was separated for determination of: Serum glucose, Lipid profile: Total Cholesterol, tri- glycerides, high density lipoprotein (HDL-C), low density lipo protein (LDL-C), very low density lipo protein (VLDL-C), urea, creatinine, uric acid, alanine amino transferase (ALT) and asparete amino transferase (AST).

At the same time, the organs: Liver, heart, spleen, kidney and lungs were removed, washed in saline solution, wiped by filter paper and weighted.

The obtained results revealed that, treatment by the best result was recorded for group 5 (hyperglycemic rats fed on rams extract 5% ) which led to significant decrease in body weight gain, feed intake, feed efficiency ratio, serum glucose, (TC), (TG), (LDL-C), (VLDL-C), a significant increase of (HDL-C) was observed, and Liver and kidney functions were also improved.

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