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Antimicrobial activity of Lepidium sativum against multi-drug resistant and sensitive pseudomonas aeruginosa : a microbiological study from Khartoum state, Sudan
Joint Authors
Arbab, Muhammad Husayn
Ahmad, Najla Muhammad
Mubarak, Akram Khalid
Muhammad, Sarah al-Shaykh
Kabbash, Ahmad Said
Barakah, Abu Bakr Agbash
Source
al-Kindy College Medical Journal
Issue
Vol. 18, Issue 2 (31 Aug. 2022), pp.96-100, 5 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2022-08-31
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Background: L.
sativum, are traditionally used for the treatment of various diseases and thought to have medicinal value.
Isolates from many part of the world is now multidrug resistant.
Therefore, there is an urgent need to look for and test an alternative herbal drug.
Objective: The present study aimed to evaluate the antibacterial activity of L.
Sativum seed extract against multi drug resistant (MDR) and sensitive Pseudomonas aeruginosa clinical isolates.
Subjects and Methods: An ethanolic and aqueous stock extracts were prepared from L.
sativum seed plant then serial dilutions were prepared and the obtained concentrations (50, 25, 12.5 and 6.2 mg/ml) were tested against 30 multidrug-resistant and 35 sensitive clinical isolates of Pseudomonas aeruginosa using wells diffusion method.
Results: It was found that L.
sativum seed extracts had antimicrobial activity against MDR and sensitive isolates at different concentrations of 100, 50 and 25 according to the mean ± SD (standard deviation) of the maximum zones of inhibition.
The total number of isolates that were sensitive to both extracts were 49/130 (37%) which represented 17/60 (28.3%) MDR and 32/70 (45.7%) sensitive isolates.
The aqueous extract exhibited more inhibitory effect than ethanolic extract 43 (66%) vs.
6 (9%) against the examined isolates (n=65).
Conclusion: The study concluded that the L.
sativum extracts had an antibacterial activity against the susceptible and MDR isolates which may enable it to be used an alternative treatment for medicinal purposes.
American Psychological Association (APA)
Mubarak, Akram Khalid& Arbab, Muhammad Husayn& Muhammad, Sarah al-Shaykh& Kabbash, Ahmad Said& Barakah, Abu Bakr Agbash& Ahmad, Najla Muhammad. 2022. Antimicrobial activity of Lepidium sativum against multi-drug resistant and sensitive pseudomonas aeruginosa : a microbiological study from Khartoum state, Sudan. al-Kindy College Medical Journal،Vol. 18, no. 2, pp.96-100.
https://search.emarefa.net/detail/BIM-1493239
Modern Language Association (MLA)
Mubarak, Akram Khalid…[et al.]. Antimicrobial activity of Lepidium sativum against multi-drug resistant and sensitive pseudomonas aeruginosa : a microbiological study from Khartoum state, Sudan. al-Kindy College Medical Journal Vol. 18, no. 2 (Aug. 2022), pp.96-100.
https://search.emarefa.net/detail/BIM-1493239
American Medical Association (AMA)
Mubarak, Akram Khalid& Arbab, Muhammad Husayn& Muhammad, Sarah al-Shaykh& Kabbash, Ahmad Said& Barakah, Abu Bakr Agbash& Ahmad, Najla Muhammad. Antimicrobial activity of Lepidium sativum against multi-drug resistant and sensitive pseudomonas aeruginosa : a microbiological study from Khartoum state, Sudan. al-Kindy College Medical Journal. 2022. Vol. 18, no. 2, pp.96-100.
https://search.emarefa.net/detail/BIM-1493239
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 99-100
Record ID
BIM-1493239