Production, purification, and identification of Glycine, N-(m-anisoyl)-methyl ester from Pseudomonas aeruginosa with antimicrobial and anticancer activities
Joint Authors
Abed, Nermine N.
Abd al-Latif, Sawsan
Mahfuz, Amira Y.
Dasuqi, Enayat M.
Abd al-Hamid, Dalya K.
Source
Issue
Vol. 48, Issue 3 (31 Jul. 2021), pp.1-12, 12 p.
Publisher
Kuwait University Academic Publication Council
Publication Date
2021-07-31
Country of Publication
Kuwait
No. of Pages
12
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
The present research is a trial to extract antimicrobial and anticancer substance(s) from Pseudomonas aeruginosa.
The bacterial isolate S1B20 exhibited the highest antimicrobial activity that was identified based on 16S rRNA gene sequence as Pseudomonas aeruginosa MG429777.
Extraction of various antimicrobial substance(s) (both proteinous and nonproteinous substances) were carried out.
Chloroform was established to be the strongest solvent for extraction of the antimicrobial substance, while the 60% ammonium sulfate saturation stage was the brightest to obtain active bacteriocin fraction.
The molecular weight of the refined bacteriocins estimated as 124 kDa.
Qualitative and quantitative results of GC-mass spectral analysis and IR spectroscopy of non-proteinous and proteinous antimicrobial agents were Oxime methoxyphenyl and Glycine, N-(m-anisoyl)-methyl ester.
The research concerned the proteinous compound and proved to have a distinct antibacterial and antitumor force against three carcinoma cell lines.
American Psychological Association (APA)
Abd al-Latif, Sawsan& Abed, Nermine N.& Mahfuz, Amira Y.& Dasuqi, Enayat M.& Abd al-Hamid, Dalya K.. 2021. Production, purification, and identification of Glycine, N-(m-anisoyl)-methyl ester from Pseudomonas aeruginosa with antimicrobial and anticancer activities. Kuwait Journal of Science،Vol. 48, no. 3, pp.1-12.
https://search.emarefa.net/detail/BIM-1503310
Modern Language Association (MLA)
Abd al-Latif, Sawsan…[et al.]. Production, purification, and identification of Glycine, N-(m-anisoyl)-methyl ester from Pseudomonas aeruginosa with antimicrobial and anticancer activities. Kuwait Journal of Science Vol. 48, no. 3 (Jul. 2021), pp.1-12.
https://search.emarefa.net/detail/BIM-1503310
American Medical Association (AMA)
Abd al-Latif, Sawsan& Abed, Nermine N.& Mahfuz, Amira Y.& Dasuqi, Enayat M.& Abd al-Hamid, Dalya K.. Production, purification, and identification of Glycine, N-(m-anisoyl)-methyl ester from Pseudomonas aeruginosa with antimicrobial and anticancer activities. Kuwait Journal of Science. 2021. Vol. 48, no. 3, pp.1-12.
https://search.emarefa.net/detail/BIM-1503310
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 10-12
Record ID
BIM-1503310