Sensitivity analysis of solute kinetics in a four compartmental model for hemodialysis patients
Joint Authors
Panni, Usman Salim Khan
Kausar, Nisrin
Anjum, Rukhshanda
Munir, Muhammad
Source
Issue
Vol. 48, Issue 3 (31 Jul. 2021), pp.1-10, 10 p.
Publisher
Kuwait University Academic Publication Council
Publication Date
2021-07-31
Country of Publication
Kuwait
No. of Pages
10
Main Subjects
Abstract EN
Sensitivity Analysis of the most advanced four compartmental mathematical model explaining solute kinetic in the hemodialysis patients was performed on the basis of the data collected from six patients with different Body Mass Indices (BMIs).
The toxin concentration in all compartments increases with the decrease in the BMIs of the patients.
The clearance rate, kclear, and the volume of extracellular compartment, VE, are the most sensitive while the volume of the muscle tissue compartment, VMT, and the clearance rate, kMT, are the least sensitive parameters during dialytic interval.
The production rate, G, and the volume of the extracellular compartment, VE, are the most sensitive while kclear and kE, AT are the least sensitive parameters of all parameters during the interdialytic interval.
The overall production rate, G, remains more sensitive than the clearance rate, kclear during one complete cycle
American Psychological Association (APA)
Munir, Muhammad& Panni, Usman Salim Khan& Kausar, Nisrin& Anjum, Rukhshanda. 2021. Sensitivity analysis of solute kinetics in a four compartmental model for hemodialysis patients. Kuwait Journal of Science،Vol. 48, no. 3, pp.1-10.
https://search.emarefa.net/detail/BIM-1503366
Modern Language Association (MLA)
Panni, Usman Salim Khan…[et al.]. Sensitivity analysis of solute kinetics in a four compartmental model for hemodialysis patients. Kuwait Journal of Science Vol. 48, no. 3 (Jul. 2021), pp.1-10.
https://search.emarefa.net/detail/BIM-1503366
American Medical Association (AMA)
Munir, Muhammad& Panni, Usman Salim Khan& Kausar, Nisrin& Anjum, Rukhshanda. Sensitivity analysis of solute kinetics in a four compartmental model for hemodialysis patients. Kuwait Journal of Science. 2021. Vol. 48, no. 3, pp.1-10.
https://search.emarefa.net/detail/BIM-1503366
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 9
Record ID
BIM-1503366