Using of 2-aminothiazole diazotised in spectrophotometric estimation of cefadroxil in dosage
Joint Authors
Sulayman, Aminah Dawud
Uthman, Nabil Subayh
Source
African Journal of Advanced Pure and Applied Sciences
Issue
Vol. 2, Issue 2 (30 Apr. 2023), pp.43-49, 7 p.
Publisher
African Academy of Advanced Studies
Publication Date
2023-04-30
Country of Publication
Libya
No. of Pages
7
Main Subjects
Abstract EN
A sensitive and simple spectrophotometric method was proposed to estimate cefadroxil in pure and capsule form.
the colored product was achieved in two steps, the first step included diazotization of 2-aminothiazole with acidic NaNO2 at 0-5°C and the second step included coupling of diazotization 2-aminothiazole with cefadroxil, the orange-colored azo dye has a maximum absorption at a wavelength of 503 nm.
Beer's law was obeyed at ranging of concentrations from 1 to 12.5 μg/ml with a determination coefficient of 0.9945.
a stoichiometric ratio of the reaction of diazotized 2-aminothiazole with cefadroxil was 1:1.
the application for determination of cefadroxil in dosage form (capsule) via the suggested method gave accepted analytical results.
American Psychological Association (APA)
Sulayman, Aminah Dawud& Uthman, Nabil Subayh. 2023. Using of 2-aminothiazole diazotised in spectrophotometric estimation of cefadroxil in dosage. African Journal of Advanced Pure and Applied Sciences،Vol. 2, no. 2, pp.43-49.
https://search.emarefa.net/detail/BIM-1506830
Modern Language Association (MLA)
Sulayman, Aminah Dawud& Uthman, Nabil Subayh. Using of 2-aminothiazole diazotised in spectrophotometric estimation of cefadroxil in dosage. African Journal of Advanced Pure and Applied Sciences Vol. 2, no. 2 (Apr. / Jun. 2023), pp.43-49.
https://search.emarefa.net/detail/BIM-1506830
American Medical Association (AMA)
Sulayman, Aminah Dawud& Uthman, Nabil Subayh. Using of 2-aminothiazole diazotised in spectrophotometric estimation of cefadroxil in dosage. African Journal of Advanced Pure and Applied Sciences. 2023. Vol. 2, no. 2, pp.43-49.
https://search.emarefa.net/detail/BIM-1506830
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 49
Record ID
BIM-1506830