Therapeutic effect of purple coneflower (Echinacea purpurea L.)‎ on rats with immune dysfunction

Abstract EN

The goal of this research is to examine how administration of Echinacea affects several blood parameters and immunological functioning in mice.

thirty albino male mice weighing 180 ± 5 g were utilized in this research.

the 1st group (n = 6) was fed a basic diet, groups 2-5 were injected with cyclosporine (CSA 50) mg for 21 days.

groups 3-5 were fed Echinacea powder at three levels (150, 300, and 450 g / kg diet), respectively.

the active components of Echinacea powder were estimate.

histopathology of the spleen was performed.

the results of the active components of the Echinacea plant recorded the presence of many important compounds.

the results indicated that groups of mice fed with Echinacea had a significant elevation in immune parameters (p < 0.05).

the average IGM and IGG value of mice fed with Echinacea elevated contrasted with the positive control group.

blood measurements were significantly elevated (p < 0.05) for the groups assumed Echinacea in the diet.

however, the white blood cell count decreased significantly.

however, a significant increase in BWG, feed quantity, and feed efficiency ratio (FER) was observed for the tested groups contrasted with the control group.

the findings also revealed a significant elevation in the levels of RBCs & hemoglobin as opposed to the positive control group.

there was an improvement in liver enzymes in the groups fed with Echinacea as opposed to the positive control group.

it can be deduced that Echinacea stimulates the immune system of mice with immune disorders.