Heterocyles XV . : one-pot synthesis of indenylpyrimidine-2-ones
Other Title(s)
الحلقات غير المتجانسة (15) : اصطناع مركبات اندينايل بيريميدين-2-اون بخطوة واحدة
Author
Source
Issue
Vol. 1, Issue 2 (31 Mar. 1997), pp.5-20, 16 p.
Publisher
Publication Date
1997-03-31
Country of Publication
Jordan
No. of Pages
16
Main Subjects
Abstract AR
يؤدي تكاثف 1–اندانون و الالدهيدات الأروماتية (K–Ia) مع اليوريا التي تكون ثنائي هيدرو البريميدينونات (K–IIa).
و قد تمت أستلة و برومة المركبات (III)، (IV) على التوالي.
أما إزالة الهيدروجين من المركبات (II) فقد أنتجت البيريميدينونات (V) المقابلة.
هذا و قد جرى إثبات تركيب جميع هذه النواتج بالطرق الكيميائية و الطيفية.
Abstract EN
Condensation of 1- indanone , aryl aldehydes (Ia-K) and urea revealed the formation of the corresponding dihydropyrimidinones (IIa - K).
These were acetylated and brominated to give compounds (IID and (IV) respectively Dehydrogenation of (II) gave the corresponding pyrimidinones (V) The Structures of the products (II - V)were substantiated by chemical and spectral methods .
In a previous Work , 1- indanone was reacted with guanidine to produce 2- amino - indenylpyrimidines (1) On the other hand, indenylpyrimidine - 2 - ones were previously prepared through a multi - step synthesis (2,3) .
The present investigation describes a one - pot synthesis of some new dihydropyrimidinones (IIa - K) .
Thus 1- indanone and urea were condensed with aryl aldehydes (Ia - K) to produce the corresponding 4 - atyl - 3,4 - dihydro - 5 tHl - indenyl (1,2 -e) pyrimidin - 2 (IH) ones (IIa - K) (2,3) .
The structure of these products was substantiated by chemical and spectral
American Psychological Association (APA)
al-Rayyis, Nizar Rabah. 1997. Heterocyles XV . : one-pot synthesis of indenylpyrimidine-2-ones. AL-Basaer،Vol. 1, no. 2, pp.5-20.
https://search.emarefa.net/detail/BIM-186679
Modern Language Association (MLA)
al-Rayyis, Nizar Rabah. Heterocyles XV . : one-pot synthesis of indenylpyrimidine-2-ones. AL-Basaer Vol. 1, no. 2 (Mar. 1997), pp.5-20.
https://search.emarefa.net/detail/BIM-186679
American Medical Association (AMA)
al-Rayyis, Nizar Rabah. Heterocyles XV . : one-pot synthesis of indenylpyrimidine-2-ones. AL-Basaer. 1997. Vol. 1, no. 2, pp.5-20.
https://search.emarefa.net/detail/BIM-186679
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 11-120
Record ID
BIM-186679