Poisoning with hair-dye containing paraphenylene diamine : ten years experience
Joint Authors
Babiker, Muhammad
Fesseha, Solomon
Fadl Allah, Mirghani
Nasr, Muhammad al-Mahdi
Balilah, Muhammad Hasan
Musa, Abd Al-Rahman Muhammad
Sulayman, Salma Muhammad
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 6, Issue 3 (30 Jun. 1995), pp.286-289, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
1995-06-30
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
Abstract EN
Hair-dye containing paraphenylene diamine (PPD) is widely used and this compound is known to be toxic, when ingested, to several organs including the kidney.
In this study, we reviewed 150 cases presenting to Khartoum Teaching Hospital with PPD poisoning over a period of 10 years.
The clinical features commonly involved the gastrointestinal tract, skin and eyes.
Nearly all the patients had angioneurotic edema and some cases developed flaccid paraplegia or paraperesis.
With regards to the renal involvement, we observed that 90 of the 150 study cases (60%) developed acute renal failure (ARF) requiring dialysis.
The mean period on dialysis was 15 days (range 1-42 days).
All patients recovered normal renal function.
In order to exclude permanent glomerular damage following overdose of PPD, 20 patients were subjected to renal biopsy following recovery from ARF.
None had evidence of glomerular injury.
On the other hand, three patients who had chronic (skin) contact with the dye and one patient who recovered from ARF a year earlier showed evidence of focal segmental glomerulosclerosis on renal biopsy.
We conclude that hair-dye containing PPD can cause severe side effects particularly after oral ingestion.
Its use should be discouraged and public attention should be drawn in this regard.
American Psychological Association (APA)
Sulayman, Salma Muhammad& Fadl Allah, Mirghani& Nasr, Muhammad al-Mahdi& Balilah, Muhammad Hasan& Fesseha, Solomon& Babiker, Muhammad…[et al.]. 1995. Poisoning with hair-dye containing paraphenylene diamine : ten years experience. Saudi Journal of Kidney Diseases and Transplantation،Vol. 6, no. 3, pp.286-289.
https://search.emarefa.net/detail/BIM-211705
Modern Language Association (MLA)
Sulayman, Salma Muhammad…[et al.]. Poisoning with hair-dye containing paraphenylene diamine : ten years experience. Saudi Journal of Kidney Diseases and Transplantation Vol. 5, no. 2 (December 1994), pp.286-289.
https://search.emarefa.net/detail/BIM-211705
American Medical Association (AMA)
Sulayman, Salma Muhammad& Fadl Allah, Mirghani& Nasr, Muhammad al-Mahdi& Balilah, Muhammad Hasan& Fesseha, Solomon& Babiker, Muhammad…[et al.]. Poisoning with hair-dye containing paraphenylene diamine : ten years experience. Saudi Journal of Kidney Diseases and Transplantation. 1995. Vol. 6, no. 3, pp.286-289.
https://search.emarefa.net/detail/BIM-211705
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 289
Record ID
BIM-211705